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Enzymes

  • METHYLATION CYCLE, GENETICS, B VITAMINS

    Dr. Hank Liers, PhD geneticsI previously published "Homocysteine Genetics – Coenzyme B Vitamins" in which I considered in-depth how homocysteine (an intermediate chemical in the Methylation Cycle) is formed from methionine, how genetics affects the metabolic pathways, and how B vitamins are used in metabolic pathways. I also wrote "Folate Ingredients – Folinic Acid & 5-MTHF" which discussed how coenzyme folate vitamins are far superior to the synthetic folic acid form. In today's article, I take a broader view of the topic that encompasses the Methylation Cycle, genetics, and B vitamins.

    THE METHYLATION CYCLE

    The Methylation Cycle is considered to be one of the most important metabolic pathways in the human body. Its most important function is to provide methyl groups via SAM (S-adenosyl methionine) to hundreds of different body substrates. Methylation is continually occurring in the body, transforming many millions of molecules throughout the body every second. Molecules receive methyl groups, then separate and recombine continuously, transforming and reforming constantly in the ongoing process of life!

    As a reminder of the pathways involved in the Methylation Cycle, the following figure provides a flow chart showing the details.

    Methylation Cycle

    Figure 1. Metabolic Pathways in Methylation Cycle

    A key purpose of this cycle is to provide methyl groups (CH3) needed by a broad range of of body functions (over 200 different functions). Examples include:

    1. Influences the genetic expression that parents give their children and helps guide the development of the embryo.
    2. Is needed by the nervous system to produce neurotransmitters and maintain the nerves.
    3. Mobilizes fats and cholesterol so they do not accumulate where they are harmful, such as the arteries and liver.
    4. Regulates hormones, including, estrogen, adrenaline, and melatonin.
    5. Detoxifies harmful chemicals and histamine a prime substance involved in inflammation.
    6. Helps repair damaged proteins in the cells so they can function properly.
    7. Protects the DNA in the genome (genetic code) to reduce the chances of mutation.
    8. Creates antioxidants used in the antioxidant defense system.

    DESCRIPTION OF PATHWAYS WITHIN THE METHYLATION CYCLE

    The overall flow of the Methylation Cycle begins with dietary methionine (an essential amino acid) which combines with ATP (adenosine triphosphate - body energy) to form SAM (S-adenosyl methionine) – the common cosubstrate involved in methyl group transfers, transsulfuration, and aminopropylation. When SAM transfers a methyl group to a body chemical the residue from this reaction leads to the production of homocysteine.

    Homocysteine can be converted in the transsulfuration pathway that requires coenzyme vitamin B6 to produce cysteine, glutathione, taurine, and sulfates. These sulfur containing substances provide important antioxidant protection and detoxification functions in the body.

    Homocysteine can be converted back to methionine through the betaine (trimethyl glycine) pathway which requires zinc and magnesium. This pathway also requires dietary betaine or choline which the body can convert into betaine.

    Also, homocysteine can be converted back to methionine via the remethylation pathway which requires 5-MTHF, coenzyme vitamin B2 and methylcobalamin (B12).

    GENETICS

    It is important to understand that each of the pathways described above are able to be executed only in the presence of enzymes (shown in blue boxes in the diagram) created by specific genes in your genetic code. For example, Betaine-Homocysteine S-Methyltransferase (BHMT) is the enzyme required in the betaine pathway, Cystathione Beta Synthase (CBS) is the enzyme required in the transsulfuration pathway, and Methylenetetrahydrofolate Reductase (MTHFR) and Methionine Synthase (MS) are enzymes required in the remethylation pathway.

    Assuming that you have perfect genetics (no mutations, SNPs, free radical damage, insertions/deletions, etc.), the proper functioning of these pathways are still subjected to the fact that the required vitamins and minerals (vitamin B6, vitamin B2, Folate, vitamin B12, zinc, magnesium, and betaine) need to be provided by your diet or from supplements for the body to function correctly.

    In addition, exposure to high levels of toxins from your environment and high levels of stress require that the nutritional needs will be even higher for the pathways to work properly. For example, exposure to high levels of toxins requires that the transsulfuration pathway be more active possibly reducing the amount of available methionine to support necessary methyl transfer reactions.

    For these reasons alone the consensus of knowledgeable practitioners is that you should be eating an organic whole foods diet, taking appropriate nutritional supplements, avoiding and eliminating toxins from food, water, and air (living in a clean environment), and avoiding an unduly stressful life. All of these actions fall into the category of Epigenetics which you generally have control over!! Doing these things alone could significantly balance the functioning of your Methylation Cycle and improve your health.

    Unfortunately, few people have perfect genetics which often causes the various pathways in the Methylation Cycle to become imbalanced and unable to correct the dysregulation imposed upon the body. For example, the enzyme MTHFR can have heterozygous (single chromosome) genetic variations in up to 50% of certain populations and homozygous genetic variations (both chromosomes) in 10% or more of certain populations.

    Some disorders that researchers have associated with MTHFR genetic variations include:

    • Alzheimer’s disease
    • Asthma
    • Atherosclerosis
    • Autism
    • Bipolar disorder
    • Bladder issues
    • Blood clots
    • Breast problems
    • Chemical sensitivity
    • Chronic fatigue syndrome
    • Down syndrome
    • Epilepsy
    • Fibromyalgia
    • Gastric problems
    • Glaucoma
    • Heart murmurs
    • High blood pressure
    • Irritable bowel syndrome
    • Leukemia
    • Male infertility
    • Methotrexate toxicity
    • Migraines with aura
    • Multiple sclerosis
    • Myocardial infarction
    • Nitrous oxide toxicity
    • Parkinson’s disease
    • Pulmonary embolisms
    • Schizophrenia
    • Stroke
    • Thyroid issues
    • Unexplained neurologic disease
    • Vascular dementia

    This extensive list is highly significant and tells us that it is very important to have  genetic testing done for the genes/enzymes in the Methylation Cycle pathway. I prefer the BodySync genetic test which evaluates the key Methylation Cycle genes plus many other important genes in a single test.

    B VITAMINS AND MINERALS

    We are strong believers that everyone should start their nutritional program by eating a balanced, organic, whole foods diet. We have been doing this ourselves for the past 30 years. Unfortunately, only a small percentage of people follow this advice and in most cases this leads to poor nutritional status that does not adequately support the body's needs. This is especially true with respect to obtaining the nutrients needed to support the Methylation Cycle.

    Nine of our family members and associates have taken the BodySync genetic test which evaluates the condition of 45 different enzymes including CBS, MTHFR (2 variations), MTR (related to B12 and 5-MTHF as they relate to methionine synthase - MS), and MTRR (related to maintaining B12 levels needed by the MTR enzyme). In every case the results showed at least 2 and up to 4 enzymes had genetic variations. These results indicate that the nutritional requirements for folate as 5-MTHF, vitamin B12 as methylcobalamin, vitamin B6, vitamin B2, magnesium and zinc will likely be significantly greater than normal.

    Given the above information, it seems essential for good health to take nutritional supplements that provide the important nutrients. Below I will discuss various formulas that I have developed and refined over many years that are useful especially for the Methylation Cycle.

    Please note that Health Products Distributors, Inc.  (HPDI) is the preferred supplier of nutritional supplements by the BodySync genetic testing company.

    MULTIVITAMINS

    When looking at the total needs the body has for nutrients that the body does not produce, including fat soluble vitamins (A, D (some), E, K1 and K2), vitamin C, B vitamins (B1, B2, B3, B5, B6, folate, B12, biotin, choline, and inositol), minerals (Ca, Mg, Zn, Se, Cu, Mn, Cr, Mo, K, boron, and vanadium), and betaine it only seems wise to include as a top priority a Multivitamin that includes all of these in what I term therapeutic amounts (carefully selected after evaluating thousands of research studies carried out over many years.)

    In this context, it is important to recognize that every enzymatic reaction in the body requires mineral cofactors in order to carry out its function. A good multivitamin provides many of these required minerals.

    Additionally, the multivitamin should contain ingredient forms that research has confirmed to be the most absorbable and usable by the body. These include coenzyme B vitamins, Krebs cycle (citrate, alpha-ketoglutarate, succinate, fumarate, & malate) minerals, and amino acid chelates.

    In the context of supporting the Methylation Cycle we are looking for specific forms and amounts of B vitamins that can adequately provide the body's needs. The means that there should be coenzyme folate as 5-MTHF of at least 400 mcg, coenzyme vitamin B-12 as methylcobalamin of at least 200 mcg, Vitamin B6 (including significant amounts of pyridoxal 5' phosphate) of at least 40 mg, and Vitamin B2 (including significant amounts of riboflavin 5' phosphate) of at least 25 mg. In addition, magnesium (100 mg) and zinc (at least 20 mg) should be provided.

    Please note that the body's requirements for magnesium is generally accepted by nutritional experts to be higher than 400 mg daily (and as high as 1,000 mg daily). For this reason we generally recommend that a person take supplemental magnesium (such as HPDI's MYO-MAG) at levels over 400 mg daily.

    The two multivitamin formulas Health Products Distributors provides for adults that meet these requirements (and more) are the Hank & Brian's Mighty Multi-Vite and Multi Two (in both capsule and tablet forms). Click on the bottles below for technical details.

    Hank & Brian's Mighty Multi-Vite multivitamin methylation cycle

    Multi Two Caps or Tablets methylation cycle

    B COMPLEX

    In situations where significant genetic variations are present it may be wise to add a B COMPLEX supplement to the MULTIVITAMIN to provide even larger amounts of the needed B vitamins. HPDI provides a B-Complex-50 product that includes significant amounts of coenzyme forms and contains 50 mg of Vitamin B1, 50 mg of Vitamin B2, 100 mg of Vitamin B3, 50 mg of Vitamin B6, 500 mcg of coenzyme folate (both folinic acid and 5-MTHF), 100 mcg of B12 (both methylcobalamin and hydroxocobalmin), 50 mg of Vitamin B5 (pantothenic acid), 500 mg of Biotin, 50 mg of choline, and 50 mg of inositol. Click on the bottle below for technical details.

    B-Complex-50 full spectrum B vitamins with coenzyme forms methylation cycle

    FOLATE AS 5-MTHF

    In situations where an inadequate diet is present and genetic testing indicates an MTHFR variation (especially a homozygous variation) Health Products Distributors provides a 5-MTHF folate supplement that easily absorbs into the body and can be directly used in combination with Vitamin B12 to convert homocysteine to methionine. Click on the bottle below for technical details.

    5-MTHF 1 mg in veggie cap methylation cycle 5-MTHF 1 mg in veggie cap

    B-12 as METHYLCOBALAMIN

    It is often the case for older patients and vegetarians that Vitamin B12 is deficient. In these cases it is wise to supplement with a significant amount of methylcobalamin to ensure that the Methylation Cycle has sufficient to effectively convert homocysteine into methionine. Health Products Distributors Vitamin B12 contains 5 mg of methylcobalamin in sublingual lozenge form that supports excellent absorption even if swallowed and absorbed by diffusion. Click on the bottle below for technical details.

    Vitamin B-12 5 mg methylcobalamin sublingual lozenge methylation cycle Vitamin B-12 – 5 mg Methylcobalamin sublingual lozenge.

    MINERALS

    Magnesium and zinc are two important minerals used in the betaine pathway of the Methylation Cycle in which homocysteine is converted back to methionine.

    In the body magnesium is involved in more than 400 essential metabolic reactions and is required by the adenosine triphosphate (ATP)-synthesizing protein in mitochondria. ATP, the molecule that provides energy for almost all metabolic processes, exists primarily as a complex with magnesium (MgATP). Therefore, it also is involved in converting methionine to SAM.

    Over 300 different enzymes depend on zinc for their ability to catalyze vital chemical reactions. Zinc-dependent enzymes can be found in all known classes of enzymes.

    Health Products Distributors provides 100 mg magnesium/vcap in its MYO-MAG supplement which is especially important in increasing ATP in the Krebs Cycle. This product also contains vitamin B1, vitamin B2, and vitamin B6 with substantial amounts of coenzyme forms and manganese. Click on the bottle below for technical details.

    MYO-MAG with 100 mg magnesium per serving key B vitamins methylation cycle MYO-MAG with 100 mg magnesium per serving and key B vitamins.

    Health Products Distributors provides 25 mg zinc/serving in its Double Zinc Plus supplement. This formula provides zinc in the picolinate and citrate forms as well as 3 mg of P5P (coenzyme B6). Click on the bottle below for technical details.

    Double Zinc Plus supplement with P5P and 25 mg zinc methylation cycle Double Zinc Plus supplement with P5P and 25 mg zinc

    SUMMARY

    The Methylation Cycle is recognized as one of the most important metabolic pathways in the human body. When not properly supported by key B vitamins and minerals, the Methylation Cycle can become severely imbalanced which can lead to a very wide range of poor health conditions. Furthermore, genetic variations in the genes that produce important enzymes allowing the Methylation Cycle to function correctly lead to even further imbalances and greater possibility for conditions of poor health.

    In this article, I have provided insight into how the Methylation Cycle works and how it can be significantly supported by lifestyle changes regarding diet and environment (Epigenetics) and by specific B vitamins and mineral supplements that I have developed over many years. In addition, we have shown that knowledge gained from genetic testing can further provide a critical understanding of your specific needs so that your health can be optimized.

    RELATED HPDI BLOG ARTICLES

    GENETICS, EPIGENETICS & HUMAN BIOLOGY

    Homocysteine Genetics – Coenzyme B Vitamins

     

  • ELECTROMAGNETIC FIELDS (EMF) AND NUTRITIONAL SUPPLEMENTS

    Fred Liers PhD EMF electromagnetic fields nutritional supplementsWe live in a digital world enjoying convenient and limitless access to people, information, and the Internet of Things. What could be the downside? EMF for one.

    What is EMF? EMF stands for "Electromagnetic Fields." Electromagnetic fields encompass an entire spectrum of waves from extremely low frequencies (ELF) and visible light to ultra-high frequencies, such as cosmic rays (ionizing radiation).

    What I refer to as "EMF" is the non-ionizing radiation to which we are exposed from cell phones and cell-phone towers, Wi-Fi, cellular data, Bluetooth, smart meters, computers, solar panel inverters, AC-to-DC transformers, power lines, and signals from other digital devices.

    Is EMF harmful? Yes, there is a large body of scientific evidence showing EMF can be extremely harmful. Plenty of evidence has existed for decades. Do a search on PubMed. The harms of EMF are not publicized to consumers, especially by companies profiting from the digital and wireless revolutions.

    The problem: every year there are more cell phone towers, Wi-Fi networks, "Smart" meters, and solar panel inverters. Soon California will mandate all new homes must have solar power, which means more EMF. Beyond this, there are millions of 5G antennas coming to your region, as part of the most powerful wireless network ever built.

    Most health care professionals don't know much about EMF and the importance of reducing exposure. However, there are a growing number of physicians who understand the dangers of EMF. They can make suggestions for lowering EMF exposure and may also refer you to EMF mitigation experts.

    There are four types of EMF building biologists generally test for in homes: 1) Radiofrequency fields (RF), 2) magnetic fields, 3) electric fields, and 4) electromagnetic interference (EMI) or "dirty electricity." All four types can cause health issues, so it is important to measure and isolate them so you can take action to reduce each type of field, respectively.

    I tested my house and office for all four types of EMF—and found all four of them at high levels. I have since mitigated them to safer levels. I continue to find ways to reduce EMF and my exposures to them.

    Ways that various types of EMF cause damage to biological systems:

    • DNA Damage - Radiofrequency (RF) radiation induces both single- and double-stranded DNA breaks in human and animal cells. When DNA breaks are not properly repaired, the long-term damage results in adverse health effects.

    • Voltage Gated Calcium Channels (VGCC) - EMF opens VGCCs causing cells to be flooded with calcium. This excess calcium disrupts multiple pathways, leading to various negative effects, including increased oxidative stress, disrupted nerve cell communication, and heart-related problems.

    • Blood Brain Barrier - EMF can open the blood-brain barrier causing toxins or other harmful substances to enter the brain, and for the brain to leak" substances it requires, such as nutrients or neurotransmitters.

    • Melatonin Hormone Reduction - EMF suppresses the production of melatonin, which is the antioxidant hormone responsible for repairing the body during sleep. When the body does not properly repair itself at night, problems can arise from immune-related conditions to premature aging.

    • Microbiome Disruption - Just as all cells—including those in our body, are electrical, the organisms in our microbiome are electrical, too. There is evidence to show that our microbiome is harmed by EMF.

    These are some of the ways that EMF can harm health. When you add them together, you begin to get a picture showing that EMF can cause significant harm to biological systems. Many scientists have suggested how EMF can contribute to almost any health condition from autism to Alzheimer's disease.

    Certain people, myself included, can immediately feel the effects of EMF exposure. Immediate or short-term effects can vary from fatigue, low-energy, and mental fogginess to head and body pains, and ringing in the ears (tinnitus). Terms used to describe the state of being sensitive to EMF are "Electromagnetic Sensitivity" and "Electromagnetic Hypersensitivity" (EHS).

    Persons who suffer from EHS may range from 2% to 7% of the population or higher. Yet, whether or not you are "EHS" or feel effects from EMF exposure, science shows your body remains subject to adverse effects, including oxidative damage. That is, just because you do not feel it, does not mean it is not harmful.

    Note: there is evidence that certain frequencies of EMF can support health. These often fall into the category of PEMF or "pulsed electromagnetic fields." Another example: the Schumann resonances (7.82 Hz – 33.8 Hz), which are natural electromagnetic resonances created by lightning discharges from the ionosphere and the surface of the earth. The Schumann resonances are natural earth frequencies to which humans and all life has been exposed for millions of years.

    MY EMF STORY

    In my case, I never really noticed any problems until I had a solar panel power system installed on my roof—on two different homes, one in 2014 and the other in 2017. In both cases, I was exposed for relatively long periods at short distances to smart meters and solar inverters, as well as solar-related Wi-Fi equipment.

    Shortly after the first installation, I noticed fatigue, inability to concentrate, and pressure in my head. I did not initially make the connection between how I was feeling and the solar installation, which included a DC to AC inverter and two smart meters. I tried to keep my analog electric meter, but the solar company told me only digital smart meters are compatible with the solar power system.

    My symptoms improved when I moved my desk away from the wall on whose opposite side the solar equipment was located. Shortly thereafter, we moved to a different home in our metropolitan area. A few years later, we had solar panels installed on our new house. I hoped to avoid symptoms similar to what I had experience previously. No such luck.

    After the second solar installation in 2017, I again experienced fatigue, inability to concentrate, as well as pain in my head. I moved my desk and unplugged the solar company's dedicated Wi-Fi unit that measures solar power generation. I felt better. But over a period of months I developed increasing low-tone tinnitus (ringing in the ears). At first it sounded like a small plane or a truck engine in the distance. The noise grew louder. Then it rumbled night and day. I realized it wasn't an engine when I discovered the noise was significantly louder in my right ear. Alarmed, I began the process of eliminating possible causes. I finally eliminated all causes—except for EMF.

    I started reading every book I could find about EMF. I read dozens of books, watched videos on the topic, and spoke to EMF experts. During this period my son chose to research EMF for science fair project. His initial idea was to build something for me (like a tinfoil helmet) to reduce my exposure. That idea evolved into measuring the EMF levels emitted by all electronics in our house.

    My son's science project would go on to regionals in our state. Yet for me, the most important thing was how it contributed to our understanding of EMF. It was a launch pad driving us deeper into research, and led to the implementation of many EMF mitigation strategies. Our entire family benefited from it.

    EMF science fair project My son Olin's 4th-grade science fair project on EMF at Southern Arizona regionals.
    EMF electromagnetic fields project Olin in front of his project board.

    It took months, but what we learned helped us take actions to mitigate EMF exposure. My tinnitus began fading and then diminished significantly so that it is not a daily issue for me. This was empowering for me because I took positive actions that made a difference in my health. The process continues because EMF in the environment is not going away. I remain vigilant. Yet, I hope my experience can help you reduce your EMF exposure, or avoid developing EMF sensitivity.

    I still use cell phones and other digital devices. But I use them less and in much smarter ways. Ways that reduce my EMF exposure. Due to my research and experience with EMF, my awareness of its dangers is such that my thinking on the topic is forever changed. I can never take EMF safety for granted. That is a good thing.

    EMF FROM SMART METERS, CELL PHONES, SOLAR INVERTERS, ETC.

    Smart meters and DC-to-AC solar inverters can produce high levels of electromagnetic interference (EMI), which is one form of EMF. For more information on EMI, read Samuel Milham's Dirty Electricity (see resources section below). After reading that book, I considered the possibility that EMI could be contributing to my problems with EMF.

    I learned that any device (like an inverter) that converts DC power (say from solar panels) into AC power (home outlets) can add unwanted forms of electricity into the AC power. Clean (60 Hz) electricity becomes polluted by electromagnetic interference. The higher the levels of this EMI or "dirty" electricity, the greater the amount of health effects.

    I obtained a broadband EMI meter from Greenwave to measure dirty electricity in my home. I measured EMI levels with the solar system running at midday. Recommended EMI levels are 25–50 millivolts. Yet, every outlet in the house measured almost 2,000 millivolts (1,986  millivolts to be precise!).

    I shut off the solar inverter (disabling it and two smart meters) to measure baseline dirty electricity. EMI levels dropped to less than 200 millivolts! This meant one thing: components of our solar system causing high levels (1700+ millivolts) of dirty electricity.

    Greenwave EMI EMF meter Greenwave's EMI meter measures dirty electricity in household wiring.

    My first solution was to purchase multiple plug-in Greenwave EMI filters. I installed them in about 25 outlets throughout my home. They reduced EMI significantly, but they did not reduce it much in the outlets nearest to area that houses the breaker box, solar inverter, and smart meters. A few outlets away from that area exhibited stubbornly high EMI (1,500+ millivolts).

    After further research, I called Satic USA. Satic is a solar company that understands that EMI can affect people. They have products designed to condition an electrical system to remove dirty electricity. I  purchased a line conditioner (Super Duty Power Perfect Box) from Satic specifically created to clean EMI from photovoltaic (PV) solar systems.

    Note: Satic describes its line conditioners primarily as energy saving devices and protectors of electrical equipment. Clean power is more efficient. Yet, clean, conditioned AC power means reduced EMI. Thus, there is a human health component built-in, if you will.

    The Power Perfect Box was installed by an electrician near our breaker box. This line conditioner (containing two harmonic rectifiers) removed many unwanted harmonics and transients induced into our homes' electrical system by the solar inverter and smart meters.

    Above all, I felt better. I could focus better. I slept better. So did everyone else in the house. And my tinnitus began to diminish.

    Satic USA EMF EMI dirty electricity Satic USA's "Power Perfect Box" is a line conditioner that directly connects to the breaker box where it "cleans" your AC power using two harmonic rectifiers.

    I highly recommend obtaining a Power Perfect Box if you have a smart meter, solar power inverter, or dirty electricity (EMI) coming from your utility. Measure baseline dirty electricity in AC outlets using a broadband EMI meter (like Greenwave) after turning off your solar inverter and and smart meters.

    Satic makes several types of Power Perfect Box. Which one you need depends on how many harmonic rectifiers your electrical system requires. They also make smaller, lower-cost in-line and plug-in EMF Eliminator devices, which act as high-capacity EMI filters. These provide less protection than a Power Perfect Box, but more than a Greenwave filter. Satic will recommend products based on your unique needs. If you contact Satic to order, ask for Alden and mention my name, then he may offer you a discount.

    At Satic's recommendation, I kept the plug-in Greenwave filters in power outlets throughout my home. Between the line conditioner and the Greenwave filters, EMI now ranges from 15 millivolts to 300 millivolts in most outlets during the day. It is lowest (10–50 millivolts) at night when the solar system is not running.

    Note: Many homes only require Greenwave plug-in filters because EMI (dirty electricity) levels are already low to moderate (100-300 millivolts), as measured by a Greenwave meter. However, a residence or office with a typical solar panel installation peaks at about 2,000 millivolts. Thus, a solar-powered home, office, or school may require a dedicated line conditioner to reduce EMI below reductions obtained by plug-in filters.

    Multiple Greenwave filters plugged into AC outlets can further reduce EMI. The combination of a line conditioner (like Satic USA's Power Perfect Box) and plug-in Greenwave filters works well to bring EMI down to safer levels.

    Greenwave EMI filters EMF Greenwave EMI filters plug into household AC outlets to reduce dirty electricity.

    NOT DONE WITH EMF YET

    Another EMF issue arose. It seems my exposure to EMF from the home solar system prior to mitigation had led to a general sensitivity to EMF from other sources. That is, even though I had reduced my exposure to fields relating to the solar panel system and its parts (smart meters, solar inverter, solar-related Wi-Fi equipment), I had nevertheless become more sensitive to EMF from cell phones, cellular phone data, Wi-Fi, Bluetooth, vehicle electronics, and other sources.

    This sensitivity meant that solving the dirty electricity (EMI) problem and dramatically reducing my tinnitus, while helpful, would not be sufficient to stop my suffering related to other EMF sources. It would take effort to identify the sources, and then remove or mitigate them.

    EMF METERS

    Meters are your best friend when it comes to measuring EMF. About the same time I found the Greenwave EMI meter—EMI is just one type of EMF—I obtained three or four meters designed to measure other types of electromagnetic fields.

    Some of my favorite meters are the Acoustimeter AM-10 (from EMFields), the Trifield 100XE (from Alpha Labs), and the ME3030B (from Gigahertz Solutions). Each meter can provide different insights into how much EMF exposure you receive from various sources.

    EMF Acoustimeter AM-10 EMFields' Acoustimeter AM-10 is sensitive, measures a wide range of frequencies (200 MHz–8 GHz), and offers a sound component.

    I began the process of measuring every type of device from iPads to cell phone chargers. I carried meters with me everywhere I went. During his science fair project, I helped my son measure and document readings from EMF sources at multiple distances. This data would be invaluable for my own mitigation efforts.

    Overall, EMF levels were far greater than I expected, and from a wider variety of sources not just mobile phones or Wi-Fi routers. For example, wireless toys and cordless phones can be among the worst offenders in the RF frequencies. Even indoor hydroponic systems can generate high levels of dirty electricity.

    Trifield 100XE meter EMF The TriField Meter 100XE is simple to use and cost-effective.

    Using my meters to obtain accurate measurements, I began reducing my exposure to all sources of EMF. The more I reduced EMF exposures, the better I felt. I noticed—and continue to notice—improvements in focus, mental energy, and overall well being.

    EMF MITIGATION SOLUTIONS

    If my EMF problems are a challenge to solve, then at least there are some upsides. My research has led me to solutions that allow me to heal and avoid symptoms. I am empowered to act upon my knowledge, and to share it.

    In many ways, my experience has been a blessing. I am now aware of EMF dangers. While I would not wish anyone to have my experience, I hope that sharing my experience can help even a few people to avoid adverse health effects of EMF.

    Here are some actions you can take that have helped me. I recommend you take these actions whether or not you feel symptoms or believe you are not affected by EMF.

    • Create a wired Internet network in the home. Computers, laptops, and HDTVs can run on hardwired Ethernet connections. Smart phones and tablets can be hardwired using Ethernet adaptor cords. Use Wi-fi routers infrequently (minimize use), or not at all. Keep routers as far away from living areas as possible.

    • Keep smart phones in airplane mode whenever possible. Minimize use of cell phones for calls. Use Air tube headsets and speaker phones whenever possible to provide distance from the device.

    • Use an anti-radiation mobile phone case (like SafeSleeve). Avoid using mobile phones in a vehicles like cars and buses (as vehicles act as Faraday cages in which signals just bounce around). Keep away from phone or tablet when downloading data. Turn off Wi-Fi and cellular data on the phone most of the time.

    • Never keep mobile phones in pockets or close to the body. Turn phone off or use airplane mode if phone must be kept in proximity to the body.

    • Turn off electronics (phones, routers, Bluetooth devices) at night. Keep cell phones and other electronics out of your bedroom. Put your router on timer switch to shut off automatically at 9 or 10 pm.

    • Use a landline phone. Yes, landline phone service still exists in most places.

    • Obtain a good general EMF meter or two, such as a Trifield, Acoustimer, Cornet, or ME3030B (Gigahertz Solutions). Test your house and your devices.

    • Test for electromagnetic interference (EMI) in household outlets using a EMI meter. Install a line conditioner and/or EMI filters (to reduce "dirty electricity"). You can obtain EMI meters and filters from Greenwave or Stetzer.

    • Shield smart meters using special "radiant barrier" anti-radiation materials, like Satic Shield (from Satic USA) or Reflectix (available at Home Depot). Place shielding on the interior wall opposite the meter. There are also metal meter cages for blocking fields coming from the face and sides of smart meter.

    • Consider an in-line conditioner for your electrical system, especially if you have a smart meter or solar panels—or measure significant amounts (300+ millivolts) of dirty electricity on your wiring. I am pleased with Satic USA's line conditioner (Power Perfect Box) that attaches to my electrical breaker box. If you contact Satic to order a line conditioner, ask for Alden and mention my name. He may give you a discount.

    • Keep a Faraday bag available for times when you want to block all signals to or from your smart phone or other devices. They are available for less than $20.

    EMF smart meter reflectix radiant barrier shield Reflectix radiant barrier is ideal for shielding smart meters.

    The more simple actions I take to reduce EMF, the better I feel. The list of actions I take to reduce EMF exposure grows weekly, it seems. Most of my symptoms have gone away. However, I have no desire to risk them coming back. Whenever possible, I avoid other people using cell phones, reduce time spent in places with Wi-Fi routers, smart meters, cell phone towers, etc.

    I have become more sensitive than some of my meters (at least sometimes), so I feel that I am nearly a kind of meter myself in terms detecting the presence and magnitude of electromagnetic fields. Even so, I am often surprised by high EMF readings using my meters. Takeaway: Relying solely on yourself (no matter how sensitive you think you are), is not the best idea.

    The most important thing you can do is to obtain a good EMF meter. Measure around your house, your devices, and appliances. Unless you actually have a meter, you will not likely optimize EMF reduction—because you can't see EMFs. If cost is an issue, certain online stores let you rent EMF meters. Get started today!

    BEST SUPPLEMENTS FOR EMF

    The first lines of defense against EMF should be increasing distance from EMF sources, and reducing duration of exposure. These make a huge difference for protecting health.

    One cannot control all sources of exposure. Neighbors have routers, smart meters, antennas, and other sources of EMF generating electronic pollution ("electrosmog"). Wi-Fi is nearly everywhere these days.

    A huge component in EMF defense is nutritional supplements. Why? Because levels of EMF to which we are commonly exposed result in oxidative stress requiring high levels of antioxidants to quench free radicals. Fortunately, HPDI produces some of the best nutritional supplements available for dealing with EMF.

    I already had a good diet and took plenty of high-quality nutritional supplements when my problems with EMF started. What I began doing differently was 1) taking generally higher doses of antioxidants and 2) targeting my antioxidant defense systems with specific antioxidant supplements.

    By focusing on meeting my higher needs for antioxidants, and by adding specific supplements known for their antioxidant capabilities, I believe I mitigate the worst adverse effects of EMF. Antioxidant supplements noticeably support my ability to function as normally as possible given both my past experiences with EMF, and the ongoing daily needs for antioxidant defense.

    I will describe the supplements I believe are most important to take for EMF exposure. I take all these supplements. I include every one of these supplements because each offers a unique benefit. Together they are the most essential formulas to help both with routine, daily exposures to EMF (like Wi-Fi and cell phones), as well as other types of exposures, such as proximity to potent EMF sources from smart meters to cell phone towers.

    ANTIOXIDANT & VITAMIN C FORMULAS

    The primary type of damage caused by EMF is oxidative stress, the most important type of nutritional supplements to help with free-radical damage are antioxidant formulas, including vitamin C and Nrf2 activator supplements. HPDI offers a complete range of antioxidant and Nrf2 activator products.

    PRO-C™ ANTIOXIDANT FORMULA

    PRO-C™ is an advanced free-radical protection formula. It performs double-duty as both a potent vitamin C formula and an superb antioxidant formula. It therefore provides important benefits when used in applications requiring Vitamin C and/or free-radical defense, e.g., protocols for general health, anti-aging, rejuvenation, etc.

    PRO-C™ contains 500 mg (833% RDA) of buffered non-GMO Vitamin C (in the form of powdered calcium, magnesium, and zinc ascorbates), as well as high-potency Grape Extract (from grape seeds, skins, and pulp), green tea extract, reduced glutathione, n-acetyl-l-cysteine (NAC), r-lipoic acid, coenzyme forms of Vitamin B2 and Vitamin B6, and selenium. Many of these ingredients are powerful Nrf2 activators.

    PRO-C antioxidant EMF

    PRO-C™ FEATURES

    • HIGHLY EFFECTIVE VITAMIN C FORMULA PLUS ANTIOXIDANTS. A Complete Vitamin C Formula and a Powerful Antioxidant Formula Combined in a Single Supplement!
    • SYNERGISTIC FREE-RADICAL QUENCHING FORMULA. PRO-C Components Work Together To Quench Free Radicals in Your Body. Vitamin C Enables Grape Extract to Function More Effectively, and Conversely Grape Extract Potentiates Vitamin C. Green Tea Extract Boosts ORAC (Oxygen Radical Absorbance Capacity) Value. Read More Below.
    • POWERFUL, NRF2 ACTIVATOR. PRO-C Components of Grape Extract, Green Tea Extract, R-Lipoic Acid, and NAC are all well known Nrf2 activators. These Nrf2 activators are able to stimulate the body's endogenous production of enzymes such as superoxidedismutase, glutathione peroxidase, catalase, and hemeoxygenase.
    • SUPERIOR, BUFFERED (NON-ACIDIC) FORM OF VITAMIN C. Mineral Ascorbates Never Acidify Your Body, Keeping You pH Balanced. Staying Alkaline Is An Important Element in Maintaining a Healthy Body.
    • RAPID ASSIMILATION. Vegetarian Capsule Form Ensures Rapid Uptake and Assimilation in the Body. You May Also Empty Capsule Contents into Water, Food, or Directly Into Your Mouth, If Desired. Mildly Tart Taste!

    If I were to take just one antioxidant/vitamn C formula, PRO-C™ would be it. However, I also take another antioxidant formula called Ultimate Protector. I believe the combination of the two superb formulas works even better for EMF exposure. That's partly because Ultimate Protector activates Nrf2 in cells allowing them to generate their own antioxidants.

    ULTIMATE PROTECTOR™
    NRF2 ACTIVATOR FORMULA

    ULTIMATE PROTECTOR™ is a next-generation cell protection formula providing Nrf2 protective enzyme activators, high levels of non-GMO Vitamin C, and a full spectrum of exceptionally high potency antioxidants (with an ORAC5.0™ value of 486,000 (per six capsules).

    ULTIMATE PROTECTOR supplies nutrients that provide anti-aging, anti-inflammatory, and pain relieving effects, as well as ultra-high levels of antioxidant protection. Damage to cells caused by free-radicals contributes to many degenerative health conditions and to the aging process. This formula effectively supports the body in combating adverse effects of free-radicals.

    Ultimate Protector antioxidant EMF

    ULTIMATE PROTECTOR™ BENEFITS

    • Anti-aging
    • Anti-inflammatory
    • Pain relief
    • Acts to support the body in the prevention of cardiovascular conditions, hypertension, and support strong immunity.
    • Ultra powerful free radical defense. Helps prevent and mitigate free radical damage that contributes to conditions of poor health.
    • Facilitates the body's internal production of antioxidant enzymes within cells by supplying natural NRF2 transcription factor activators
    • Ultra effective, high potency, best-in-class antioxidant protection

    ULTIMATE PROTECTOR™ FEATURES

    • Plant Based Nrf2 Activators Potentiate the Body's Internal Antioxidant Systems
    • Ultra-High Antioxidant Potency with an ORAC5.0™ of 486,000 (per six capsules)!
    • Complete Formula Defends Body Against All Five Major Classes of Free Radicals. Provides 30+ Fruit- and Vegetable-Based Antioxidants and Nrf2 Activators to Offer Full Spectrum Protection.
    • Synergistic Formula Combines Effects of Endogenous (Internally Produced) Antioxidants, Exogenous (externally supplied) Antioxidants, and Vitamin C
    • 100% non-GMO Ingredients (includes non-GMO Vitamin C)
    • Veggie Capsules (suitable for vegetarians and vegans)>
    • Six Capsules Daily Provides Optimal Antioxidant Protection

    ULTIMATE PROTECTOR™ contains USP-grade non-GMO Vitamin C, AnthoComplete™ (high-ORAC powder: 3000 units/g from Wild Blueberry, Wild Bilberry, Acai, Black Currant Extract, Sweet Cherry, Raspberry, Elderberry, Blackberry, Aronia, Black Soybean Hull Extract, and Blue Corn), CoffeeBerry®Forte® (high-ORAC powder: 6,000 units/g from Coffee Berry), Curcumin (standardized extract with 95% curcuminoids), Trans-Resveratrol (98% from Giant Knotweed), VitaBerry®Plus® (high-ORAC powder: 12,000 units/g from freeze-dried Grape Seed, Wild Blueberry, Wild Bilberry, Cranberry, Tart Cherry, Prune, Raspberry Seed, Strawberry, Trans-Resveratrol, and Quercetin), VitaVeggie® (high-ORAC powder: 6,000 units/g from Broccoli, Broccoli Sprouts, Tomato, Kale, Carrot, Brussels Sprouts, Onion and Spinach), and Bioperine® (a patented black pepper extract that enhances absorption of all ingredients).

    By taking Ultimate Protector along with PRO-C™ as my primary antioxidant defense formulas, I maximize my EMF protection by allowing their benefits to function synergistically for greater effect.

    OTHER FOUNDATIONAL FORMULAS

    I emphasize the importance of antioxidant formulas because they are most effective at quenching the free-radicals caused by exposure to electromagnetic fields. In reality, HPDI's antioxidant and vitamin C formulas are part of a complete system of HPDI supplements. This three-tiered system includes foundational supplements, enhancement formulas, and condition-specific formulas.

    While antioxidant supplements are most important EMF defense, the truth is that antioxidant supplements work far better when they are properly combined with other foundational supplements in the HPDI system. That is, a high-potency multivitamin, essential fatty acids, and a Rejuvenate!™ superfood.

    The case for multivitamins is abundantly clear. If you look at the list of harmful effects of EMF (above), you will see that in addition to free-radical damage, EMF harms many essential biological functions in cells. Many of these functions cause cells to require additional vitamins and minerals. These nutrients can be provided by a high-potency multivitamin that provides both optimal amounts (versus minimal amounts) of nutrients, but also proper forms (like coenzyme vitamins) that are most readily assimilated and used by the body. Such forms are immediately used and do not require conversion to usable forms.

    MULTIVITAMINS:
    HIGH-POTENCY, HIGH-PURITY

    HPDI Multivitamins include five different formulas, including a children's chewable that scales up easily for adults. Two of the primary multivitamins are Multi Two Caps and Mighty Multi-Vite (caps).

    Multi Two Caps - A comprehensive multivitamin providing optimal levels of key vitamins, minerals, and cofactors. Includes higher levels of B vitamins.

    Mighty-Multi-Vite! - Similar to Multi Two Caps, but offers higher levels of key phytonutrients turmeric, grape extract, and broccoli sprouts powder.

    HPDI's high-potency multivitamins provide:

    • B-Complex vitamins: B-Complex vitamins supports enzyme systems. Enzymes are required for all metabolic functions in the body. B vitamins are cofactors required for every enzymatic reaction.

    • Minerals. HPDI multivitamins provide 10 or more key minerals. Like B vitamins, minerals support enzyme systems. At the center is every enzyme is an important mineral necessary for its function.

    • NAC (N-Acetyl-Cysteine): NAC increases glutathione levels, which are important antioxidant defense in the body.

    • Fat-soluble vitamins A, C, D, E, and K. Fat soluble vitamins perform many essential functions, including protection of cell membranes.

    Multi Two Caps multivitamin EMF

    HPDI MULTIVITAMINS FEATURES

    • COMPLETE, BALANCED CORE NUTRITION. Full-Spectrum of Nutrients Exceptionally Balanced for Supporting Your Health. Foundational Formula Ideal for Providing Essential Foundational  Nutrition. A high-quality multivitamin is the foundation (i.e., core) for a complete nutritional supplement program.
    • RAPID AND EFFECTIVE ASSIMILATION. Incorporates Bioavailable Vitamin and Mineral Carriers Your Body Recognizes and Can Assimilate Immediately. Plus, Multiple Carriers Ensure Assimilation. Tablet or Capsule Forms Rapidly Assimilated!
    • ENERGIZING: Includes Coenzyme Form Vitamins and Krebs Cycle Bionutrients that work with your body to create high energy levels. Full-Spectrum Essential Nutrients Needed For Building, Supporting, and Maintaining Excellent Health.
    • HIGH PURITY. Among the Purest Available Multivitamin supplements. Carefully Designed To Exclude Common Allergens, and Exclude or Minimize Excipients, Additives, and Fillers.

    If I could only take a single supplement daily, it would be a multivitamin. I personally prefer HPDI's Mighty Multi-Vite!. But Multi Two actually provides higher levels of important B vitamins.

    Multivitamins are too vital not to take daily. Fortunately, you are not limited to taking a single supplement. That is why I put antioxidant and vitamin C formulas at the top of the list for protection against EMF. The truth is, however, that both a multivitamin and antioxidants are essential for foundational nutrition. You need both to ensure optimal protection from EMF. There are a few more critical nutrients you need, as well.

    ESSENTIAL FATTY ACIDS (EFA)

    Another important foundational supplement is essential fatty acids (EFA). Essential fats are critical for cellular function, cell membrane health, combating inflammatory processes, and overall health. Essential fats are necessary for cellular health. Yet, because EMF creates problems at the cellular level, it is even more vital to obtain essential fats to help cells function at their best.

    People overlook the importance of essential fats. That is, I notice that multivitamins and antioxidants are far more likely to be prioritized, and therefore taken daily. Fair enough, because I prioritize those supplements too. Yet, we neglect essential fats at our peril. That is why I take EFAs daily, too.

    IMPORTANT FUNCTIONS OF ESSENTIAL FATTY ACIDS (EFA)

    • Regulate steroid production and hormone synthesis
    • Regulate pressure in the eyes, joints, and blood vessels
    • Regulate response to pain, inflammation, and swelling
    • Mediate Immune Response
    • Regulate bodily secretions and their viscosity
    • Dilate or constrict blood vessels
    • Regulate smooth muscle and autonomic reflexes
    • Are primary constituents of cellular membranes
    • Regulate the rate at which cells divide
    • Necessary for the transport of oxygen from the red blood cells to tissues
    • Necessary for proper kidney function and fluid balance
    • Prevent red blood cells from clumping together
    • Regulate nerve transmission

    When by diet or supplementation, you consume the correct ratios and amounts of essential fatty acids, then you allow the EFAs to act in ways critical for these functions. For more detailed information, see Dr. Hank's article, "The Truth About Essential Fatty Acids" (December 2017).

    HPDI's essential fatty acids formula is Essential Fats Plus E. Essential Fats Plus E provides essential fasts in the proper amounts and ratios for good health.

    Essential Fats Plus E EMF

    Essential Fats Plus E contains eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) (important essential omega-3 fatty acids), gamma linolenic acid (GLA) (an important essential omega-6 fatty acid), and mixed tocotrienols and tocopherols (Vitamin E).

    The EPA and DHA are in the form of triglycerides derived from marine lipids (using patented flash molecular distillation) and the GLA is from cold-pressed borage seed oil. The mixed tocotrienols and tocopherols derive from rice bran oil, and are included in the softgel capsules for antioxidant protection of the polyunsaturated oils.

    Omega-3 and omega-6 fatty acids are known to play important roles in the formation of prostaglandins. The prostaglandins are important cellular regulators controlling inflammatory processes and pain in the body.

    Fish oils may be useful adjuncts in protocols for 1) Cardiovascular disease, 2) Hypertension, 3) Arthritis and inflammatory disorders, 4) Psoriasis and skin problems, 5) Diabetes mellitus, 6) Depression, and 7) Kidney disease. GLA may be a useful adjunct in protocols for 1) Multiple Sclerosis and 2) Arthritis. Research indicates that in a balanced formula there are synergistic effects between EPA, DHA, and GLA. For example, it is known that EPA inhibits the conversion of GLA into pro-inflammatory (and pain-causing) arachidonic acid.

    Research indicates that in a balanced formula there are synergistic effects between EPA, DHA, and GLA. For example, it is known that EPA inhibits the conversion of GLA into pro-inflammatory (and pain-causing) arachidonic acid.

    Because these fatty acids have many double bonds that are prone to oxidation, Vitamin E is included in the forms of mixed tocotrienols and tocopherols. In addition, these forms of Vitamin E have been shown to reduce arterial plaques and enhance blood flow, inhibit thromboxane and platelet aggregation, protect serum lipids from oxidation (including LDL and HDL), reduce carotid stenosis (narrowing) and prevent stroke, trap harmful nitrogenous radicals, act as anti-proliferative agents, and provide powerful oxidative defense for the skin.

    Essential fatty acids are considered "essential" for all the reasons described. They are so critical for proper cellular function that not having sufficient essential  fats  (or the proper ratios) can impair important processes in the body. I believe EMF exposure puts additional stress on cells such that essential fats are even more necessary. So take an EFA supplement like Essential Fasts Plus E every day.

    HYDROGEN SUPPLEMENTS

    Hydrogen supplements can be very helpful for preventing or mitigating oxidative damage by EMF. I have recently written about two hydrogen formulas that support antioxidant defenses: Megahydrate and Active H2 Ultra. (See "Hydrogen Supplements – Active H2 Ultra and Megahydrate")

    MEGAHYDRATE

    Megahydrate (powder and capsules) provides H-, or the hydrogen anion, which provides lasting antioxidant protection. It this regard, it is highly effective at quenching free radical (even better than molecular hydrogen), greatly enhances the production of ATP (cellular energy) in the body, retains its antioxidant capacity for extended periods, and is the key unlocking the potential of water as the medium for nutrient replenishment and waste removal at the cellular level.

    The active ingredient in Megahydrate is silica hydride. One very important characteristic of the antioxidant capacity of silica hydride is that it is the only antioxidant that does not turn into a free radical (i.e., oxidant) once it has neutralized a free radical by donating its electron. Negatively-charged hydrogen turns into molecular hydrogen gas and/or turns into water.

    Megahydrate antioxidant EMF

    One daily dose of Megahydrate has more antioxidant power than hundreds of glasses of fresh vegetable and fruit juices, broccoli, brussel sprouts, leafy greens, and other foods rich in antioxidants and prevents free radical damage.

    Studies show that Megahydrate increases energy production (adenosine triphosphate or ATP) by up to four times.

    BENEFITS OF MEGAHYDRATE

    • Contains Hydrating Silica Microclusters®
    • Extremely Powerful Antioxidant
    • Recycles other Key Antioxidants in the Body
    • Extremely Safe and Non-Toxic
    • Easily Accesses All Cells in the body
    • Increases Cellular ATP Production by up to a factor of 4 times
    • Readily Converts NAD+ to NADH
    • Reduces Pain & Inflammation
    • Exhibits Powerful Anti-Aging Properties
    • Protects and Repairs DNA
    • Neutralizes Harmful Toxins like Fluoride, Chlorine, etc.
    • Protects Against and Repairs Radiation Damage
    • Increases Absorption of other Supplements
    • Lowers surface tension of water you drink leading to improved detoxification
    • Removes Heavy Metals from the Body
    • Balances pH or Alkalizes the body
    • Increases Zeta Potential of Human Cells
    • Increases Cellular Hydration
    • Very Stable – Works Over Extensive Time Periods
    • Reduces Lactic Acid Buildup During Intense Workouts
    • Protects Telomeres by allowing cells to exceed the Hayflick limit by 4–5 times

    I drink Megahydrate daily in water. I find it very energizing and it seems to potentiate the other antioxidant supplements. Usually I drink it mixed with Active H2 Ultra, which provides molecular hydrogen. But sometimes I drink Megahydrate all by itself, as it is an excellent standalone hydrogen formula.

    ACTIVE H2 ULTRA

    ACTIVE H2® ULTRA is my favorite molecular hydrogen formula. In fact, I almost always add this tablet into water that is already infused with Megahydrate. That is, I believe this formula works best when taken together with Megahydrate. I like this combination "fizzy" drink so much, I created a video showing how to make it.

    Active H2 Ultra tablets provides abundant hydrogen molecules that are uniquely found in fresh, raw, living foods and are essential to any serious antioxidation program.

    A unique and patent pending combination of magnesium and supporting nutrients are the only active substances in Active H2 Ultra. This distinguishes it from the existing synthetic chemical formulas as well as the use of electrolysis (as in water ionizers) to generate molecular hydrogen.

    The natural, proven Active H2 Ultra formula consists of a proprietary blend of pure magnesium metal, malic acid, tartaric acid, stearic acid, and dextrose that act synergistically in water to generate Molecular Hydrogen and electron-rich potential (-ORP).

    Active H2 Ultra EMF

    BENEFITS OF ACTIVE H2 ULTRA

    • Unsurpassed antioxidizing effects indicated by strong negative-ORP
    • Scavenging of cytotoxic oxygen radicals and highly reactive hydroxyl radicals
    • Reduction of oxidative stress and inflammation
    • Regulation of various gene expressions and protein-phosphorylations
    • A synergistic complement to other cellular antioxidants like vitamin C, vitamin E, and glutathione
    • Enhanced endurance in daily activity and strenuous exercise
    • Clinically proven to reduce lactic acid levels during strenuous workouts
    • Reduced water cluster size for improved cellular hydration

      ACTIVE H2 ULTRA FEATURES

    • -700 mV ORP in 1 liter of pure water
    • Increases cellular hydration
    • Regular use heightens physical and mental energy
    • Supports mitochondrial ATP (energy) production
    • Alkalizing minerals (magnesium)
    • Quickly and cleanly dissolves in less than 1 minute - no waiting around for dissolution.
    • You can drink  as soon as the tablet dissolves – thereby getting greater amount of hydrogen than in tablets that take longer to dissolve.

    Hydrogen is emerging among the top super-nutrition discoveries of the 21st century. I am not waiting to gain its benefits. Just as many athletes are using it to gain a competitive advantage, I take Active H2 Ultra and Megahydrate for their effective antioxidant benefits and much more, including EMF protection. And so should you.

    RESTORE

    RESTORE is one of those products that go beyond anything else I've seen in terms of what is can do and how it does it. In fact, I recently published an article devoted solely to Restore (see "Restore Gut Health Formula + Video").

    The reason I include RESTORE in my list of top formulas for EMF exposure is because it protects the integrity of the gut barrier or tight junctions, supports the communications system in the gut microbiome, and acts as a fertilizer for the microbiome itself. These are important effects because EMF breaks down tight junctions, interferes with microbiome communications (as gut bacteria use their own weak EMF signals to communicate), and reduces microbiome health.

    restore gut health EMF

    RESTORE is a soil-derived, scientifically backed mineral supplement that creates a firewall against toxins entering the gut wall. RESTORE helps create a biological environment for "good" gut bacteria to grow and flourish in order to support improvement of overall health.

    RESTORE is not a probiotic. It is not a prebiotic. Rather, it is a carbon rich, alkaline liquid, with lignite derived trace organics and essential trace amino acids, that promotes an optimal environment in the gut. With 70% of the immune system located in the gut, this optimal gut environment leads to great gut health.

    Research has shown RESTORE to be non-toxic and to support the tight junction cells of the gut lining. Additionally, RESTORE has been shown both in the laboratory and clinically to help support the functioning of the gut barrier and improve gut health. In experiments, toxins like herbicides and gluten have been shown to degrade the gut barrier. RESTORE has been shown to promote the strengthening of the tight junction gut barrier in small and large gut membrane cells for gut health.

    One of the main elements in RESTORE is the lignite extract. Lignite comes from decomposed prehistoric matter. As plants decompose, they first form peat, which then turns into humate, then lignite, then leonardite and finally to coal. All of these are rich in carbon. One of the differences between all of these elements is the amount of time and pressure have been applied to them.

    OTHER IMPORTANT SUPPLEMENTS MITIGATING EMF EFFECTS

    My list of favorite supplements for EMF could be much longer. I will mention two other types of supplements I think can be useful for most people. One is magnesium and the other is C-60 (or Carbon-60).

    MAGNESIUM

    Magnesium is critical for supporting and enabling at least 400 enzymes in the body that are needed for the vital reactions in cells. EMF can damage or impair enzyme function. Therefore sufficient magnesium is essential for optimal cell function. One known problem is that most people are deficient in magnesium. When enzyme systems lack magnesium, they fail to properly function, resulting in many problems in the body, including lower energy production (ATP) and deficient metabolism.

    Magnesium also balances calcium in cells. When EMF causes voltage gated calcium channels (VGCC) to open flooding cells with calcium, the presence of magnesium may help because one of the functions of magnesium is preventing cellular calcium imbalances. Not to mention the role of magnesium in energy production—as energy is required to pump excess calcium out of cells.

    One of my favorite magnesium products is MYO-MAG. MYO-MAG is an advanced, synergistic magnesium formula that provides therapeutic levels of magnesium, plus nutrients that support the body's utilization of magnesium.

    MYO-MAG provides magnesium in the form of malate and diglycinate, as well as Vitamins B1, B2, and B6 (including coenzyme forms of these vitamins). The formula is buffered with a small amount of magnesium carbonate, and includes some manganese for mineral balance.

    MYO-MAG therefore is a highly effective oral magnesium supplement with benefits that include less fatigue and greater energy, improved metabolic functions, cardiovascular support, nutrition for muscles, reduced spasms or cramps, help for migraine headaches, and many others.

    The formula not only supports metabolism, but also cellular energy production (ATP) and optimal cellular function. It allows for rapid uptake and absorption of easily assimilated forms of magnesium. It also provides critical nutrients supporting energy production in the body.

    Because MYO-MAG rapidly boosts magnesium levels, individuals usually notice greater physical and mental energy, reduced fatigue, and often a greater sense of overall well being.

    Myo-Mag EMF MYO-MAG provides magnesium important for cellular energy.

    MYO-MAG contains ingredients participating in the production of ATP. One vegetarian capsule contains 100 mg of magnesium and 440 mg of l-malic acid. Vitamins B1 and B2 are included both in standard and phosphorylated forms. Also included are Vitamin B6 in its phosphorylated form only, manganese (because high levels of magnesium can deplete the body of it), magnesium carbonate (a malic acid buffer), and glycine as the carrier for a portion of the magnesium and for the manganese. MYO-MAG is contained in a vegetarian capsule to ensure rapid assimilation.

    Supplementing the diet with magnesium and malic acid may reverse conditions of low energy. Suggested daily amounts include 300–600 mg of magnesium and 1200–2400 mg of malic acid. Taking 3 to 8 MYO-MAG capsules daily can provide these amounts. Beyond this formula, HPDI offers a complete range of magnesium formulas, including Ancient Minerals topical magnesium chloride products (oil, flakes, and gel).

    CARBON-60

    Carbon-60 or C-60 is an experimental supplement providing extremely high antioxidant capacities. Carbon-60 provides research grade Carbon-60 Fullerenes (0.8 mg/ml) in organic olive oil. While this formula is formulated for research, it is known to be among the most powerful antioxidants available. The structure of the Fullerene allows for a large number of electrons to be held and repeatedly donated for the purpose of quenching free radicals. It therefore offers unrivaled  antioxidant capacity in the body.

    I will be talking a lot more about Carbon-60 in coming months. Suffice it to say that the research is showing that C-60 may be the future of antioxidant nutrition.

    CONCLUSION

    Few people have paid much attention to the dangers of EMF until recently. There is growing awareness that EMF contributes to health problems, as well as the mechanisms by which EMF damages the body. Given the rise in health conditions likely to be related to EMF exposure, it makes sense to take action now, rather than unnecessarily risking harmful effects of exposures.

    There are many actions you take to protect yourself and your family. These include turning off Wi-Fi, putting cell phones on airplane mode, shielding smart meters (or keeping your analog meters), increasing distance from EMF sources, and reducing duration of exposure.

    Taking nutritional supplements providing good levels of antioxidant nutrients and supporting metabolic functions makes a lot of sense, too. Supplements have helped me be healthier and recover faster from EMF exposures. They likely can help you and yours do the same.

    EMF damages your cells daily. Take action to protect yourself!

    RESOURCES

    Blog Articles

    HYDROGEN SUPPLEMENTS – ACTIVE H2 ULTRA AND MEGAHYDRATE

    HYDROGEN SUPPLEMENTS – MAKE HYDROGEN DRINKS

    RESTORE GUT HEALTH FORMULA + VIDEO

    THE TRUTH ABOUT ESSENTIAL FATTY ACIDS

    Products

    Foundational Supplements

    HPDI antioxidant & vitamin C formulas

    PRO-C™

    Ultimate Protector

    HPDI Multivitamins

    Multi Two

    Mighty Multi-Vite!

    Essential Fats Plus E

    Hydrogen Supplements

    Megahydrate

    Active H2 Ultra

    Gut Health Formulas

    Restore

    Myo-Mag (magnesium)

    Ancient Minerals topical magnesium

    Carbon-60

    Scientific Articles, Books, and Video

    Allen, Russ. Electrocution of America: Is Your Utility Company Out to Kill You? Kindle Edition. Glenmore Books, 2008.

    Austrian Medical Association EMF Working Group (AG-EMF). Guideline of the Austrian Medical Association for the Diagnosis and Treatment of EMF-Related Health Problems and Illnesses (EMF Syndrome). 2012. Web. Feb. 2018. <http://www.vagbrytaren.org/Guideline%20%20AG-EMF.pdf >

    Bawden-Smith, Jason. In the Dark: New Ways to Avoid the Harmful Effects of Living in a Technologically Connected World. Australia: Major Street Publishing Pty Ltd, 2016.

    Belyaev, Igor, et al. “EUROPAEN EMF Guideline 2016 for the Prevention, Diagnosis, and Treatment of EMF-Related Problems and Illnesses.” Reviews on Environmental Health, vol. 31, no. 3, 2016, pp. 363-97.

    BioInitiative Report: A Rationale for a Biologically Based Public Exposure Standard for Electromagnetic Radiation. Cindy Sage and David O. Carpenter, eds. The BioInitiative Working Group. Sage Associates, 2012. <www.bioinitiative.org>

    Blank, Martin, PhD. Overpowered: What Science Tells Us About the Dangers of Cell Phones and Other Wi-Fi Age Devices. New York: Seven Stories Press, 2015.

    Burrell, Lloyd. EMF Protection Free Report. eBook. ElectricSense: 2015.

    Burrell, Lloyd. Long Term EMF Protection: Start Feeling Better Today. eBook. ElectricSense, 2013.

    Calvente, Irene, et al. “Characterization of Indoor Extremely Low Frequency and Low Frequency Electromagnetic Fields in the INMA-Granada Cohort.” PLoS One, 2014, vol. 9, no. 9, e106666. Web. Feb 2018. <http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0106666>

    Davis, Devra, PhD, MPH. Disconnect: The Truth About Cell Phone Radiation. New York: Environmental Health Trust, 2013.

    Federal Communications Commission. Radio Frequency Safety: FCC Policy on Human Exposure to Radio Frequency Electromagnetic Fields. Web. Feb. 2018. <https://www.fcc.gov/general/radio-frequency-safety-0>

    Full Signal: The Hidden Cost of Cell Phones. DVD. Directed by Talal Jabari. Capture Productions, 2009.

    Generation Zapped. DVD. Directed by Sabine El Gemayel. Zapped Productions, 2017. <www.generationzapped.com>

    Gittleman, Ann Louise. Zapped: Why Your Cell Phone Shouldn’t be Your Alarm Clock and 1,268 Ways to Outsmart the Hazards of Electromagnetic Pollution. New York: Harper Collins, 2010.

    Halpern, Dr. Jonathan, PhD. Electromagnetic Radiation Survival Guide: Step-by-Step Solutions. Kindle Edition. CreateSpace Independent Publishing, 2014.

    Hardell, L. and C. Sage. “Biological Effects from Electromagnetic Field Exposure and Public Exposure Standards.” Biomedicine & Pharmacotherapy, vol. 62, no. 2, 2008, pp. 104-109.

    Hardell, Lennart. “World Health Organization, Radiofrequency Radiation and Health – A Hard Nut to Crack (Review).” International Journal of Oncology, vol. 51, no. 2, 2017, pp. 405-413.

    International Commission on Non-Ionizing Radiation Protection (ICNIRP). “ICNIRP Guidelines for Limiting Exposure to Time-Varying Electric, Magnetic, and Electromagnetic Fields (Up to 300 GHz).” Health Physics, vol. 74, no. 4, 1998, pp. 494-522.

    International Institute for Building Biology. Standard of Building Biology Testing Methods. IBE SBM-2008C V3.6. 2008. Web. Feb. 2018. <http://hbelc.org/pdf/standards/SBM-2008C-v3.6.pdf>

    INTERPHONE Study Group. “Brain Tumor Risk in Relation to Mobile Telephone Use: Results of the INTERPHONE International Case-Control Study.” International Journal of Epidemiology, vol. 39, no. 3, 2010, pp. 675-94.

    Johnson, Jeromy. Wireless Wake-Up Call. TEDxBerkeley. 2016.

    Kundi, M., L. Hardell, C. Sage, and E. Sobel. “Electromagnetic Fields and the Precautionary Principle.” Environmental Health Perspectives, vol. 117, no. 11, 2009, pp. A484-5.

    Michigan State University. “Electromagnetic Fields Affect Human Cells.” ScienceDaily. ScienceDaily, 16 October 2000. Web. Feb. 2018.
    >www.sciencedaily.com/releases/2000/10/001016073704.htm>

    Mild, K.H., M. Repacholi, E. Deventer, and P. Ravazzani, eds. International Workshop on EMF Hypersensitivity Conference Proceedings: Electromagnetic Hypersensitivity, 25-27 Oct. 2004, Prague, Czech Republic. Geneva, Switzerland: World Health Organization Press, 2006.

    Milham, Samuel, MD, MPH. Dirty Electricity: Electrification and the Diseases of Civilization. Second Edition. Bloomington, Indiana: iUniverse, 2012.

    Mobilize: A Film About Cell Phone Radiation. DVD. Directed by Kevin Kunze, performances by Gavin Newsom and Steve Wozniak. Dreamscape Media, 2016.

    Ober, Clinton, Steven T. Sinatra, and Martin Zucker. Earthing: The Most Important Health Discovery Ever. Colorado Springs, CO: Basic Health Publications, 2014.

    Phillips, J.L., N. P. Singh, and H. Lai. “Electromagnetic Fields and DNA Damage.” Pathophysiology, vol. 16, nos. 2-3, 2009, pp. 79-88.

    Pineault, Nicolas. The Non-Tinfoil Guide to EMFs: How to Fix Our Stupid Use of Technology. Montreal, Canada: N&G Media, Inc., 2017.

    Pinsky, Mark. The EMF Book: What You Should Know About Electromagnetic Fields, Electromagnetic Radiation, and Your Health. New York: Warner Books Incorporated, 1995.

    Plourde, Elizabeth PhD and Marcus Plourde PhD. EMF Freedom: Solutions for the 21st Century Pollution. 3rd Ed. Irvine, California: New Voice Publications, 2016.

    Resonance: Beings of Frequency. DVD. Directed by James Russell. Jansen Media, 2016.

    Simkó, M., and MO Mattisson. “Extremely Low Frequency Electromagnetic Fields as Effectors of Cellular Responses in Vitro: Possible Immune Cell Activation.” Journal of Cell Biochemistry, vol. 93, no. 1, 2004, pp. 83-92.

    Starkey, S.J. “Inaccurate Official Assessment of Radiofrequency Safety by the Advisory Group on Non-Ionising Radiation.” Reviews on Environmental Health, vol. 31, no. 1, 2016, pp. 493-503.

    Take Back Your Power: Investigating the Smart Grid. DVD. Directed by Josh del Sol. BigPitcher Films (Canada), 2013.

    Waugh, Jim. Living Safely with Electromagnetic Radiation: A Complete Guide for Protecting Your Health. Richmond Hill, Canada: Firefly Books, 2010.

    World Health Organization (WHO). Electromagnetic Fields and Public Health: Electromagnetic Hypersensitivity (EHS). Fact Sheet no. 296. 2005. <http://www.who.int/peh-emf/publications/facts/fs296/en/>

    World Health Organization (WHO). International Agency for Research on Cancer (IARC). IARC Classifies Radiofrequency Electromagnetic Fields as Possibly Carcinogenic to Humans. Press Release. 31 May 2011. <http://www.iarc.fr/en/media-centre/pr/2011/pdfs/pr208_E.pdf>

     

  • GENETICS, EPIGENETICS & HUMAN BIOLOGY

    Genetics, Epigenetics, and Human Biology

    Dr. Hank Liers, PhD geneticsWe are entering a time in which new scientific tools are available that provide clear insights regarding the causes of poor health, as well as therapies that can be used to overcome health issues. Specifically, these tools include 1) our understanding and ability to characterize the human genome, and 2) advances in the science of epigenetics showing how environmental factors significantly influence the expression of genetics and human biology.

    For many years, my company (Health Products Distributors, Inc. – "HPDI") has been involved in Rejuvenation/Healing Programs which take multiple health modalities into consideration (for information on HPDI's Rejuvenation/Healing Programs, see Additional Resources below). Our programs have generally involved the following elements:

    1. Health-Building Nutrition
      Rejuvenation begins with nutrition in the broadest sense. That is, nutrition derived from healthy foods, superfoods, supplements, dietary nucleic acids, water and fluids, as well as via the skin. Establishing health-building nutrition is foundational to rejuvenating the body, mind, and spirit.
    2. Detoxification & Preventing Toxicity
      Individuals cannot fully experience rejuvenation without having effective means for removing existing toxins form the body, or for stopping further accumulation of toxins absorbed from foods, air, water, and skin. Such toxins include everything from chemicals in foods and water to the many toxins found in homes, workplaces, personal products, and just about everywhere.
    3. Building Powerful Immunity
      Building immunity is important for health because the immune system is the means by which the body defends itself. Yet, if the best defense is a strong offense, then having a strong immunity protects us in ways beyond just defense. Building immunity is accomplished not only by nutrition, but also by utilizing herbs, immune boosting supplements, and immune-enhancing protocols.
    4. Supporting Protocols
      Certain practices and protocols powerfully support rejuvenation. These protocols include exercise, massage, saunas/hydrotherapy,  yoga, acupuncture, meditation, and others.
    5. Attitude and Commitment to Becoming Healthy
      Attitude and Commitment are foundational to your rejuvenation/healing program because having total focused intention regarding your health is essential for success. If a journey of a thousand miles begins with a single step, establishing that intention perspective is a great place to start.

    ADDING GENETICS TEST TO HPDI REJUVENATION PROGRAM

    In the last few years, we have seen how healing and wellness programs can be significantly enhanced by adding genetics testing into the mix. In fact, we have joined forces with BodySync, a company with the most advanced single genetics test available. This test characterizes 45 different genes and gene variations. The Bodysync genetics test results are combined with basic lifestyle information provided by the patient to create a complete program customized for dealing with gene variations having either harmful or helpful effects.

    The insights gleaned by taking the BodySync genetics test provides new insights into reasons a person may experience health challenges that no other method can provide. The test results and action plan also provide information regarding genetic strengths, especially related to athletic performance and weight management.

    The NutriSync test from BodySync genetics

    HPDI now adds the BodySync genetics test to the list of key elements in our rejuvenation/healing programs. In fact, we are now introducing the BodySync genetic test along with consultations to our HPDI Reseller Associates—so that health practitioners (HPs) can experience the benefits of the test for themselves— and see how genetics consulting can be added to their practice. In addition, BodySync has selected HPDI as their preferred supplier of nutritional supplements supporting the recommendations provided in their Action Plans for individuals taking the test. It is exciting to be part of this breakthrough in the practice of genetic science.

    BROAD OVERVIEW OF GENETICS, EPIGENETICS, AND HUMAN BIOLOGY

    In order to give a more complete understanding of our program for attaining excellent health, we have developed a broad scientific overview of how all the key elements are related and eventually expressed as YOU.

    The diagram below provides a broad overview of genetics, epigenetics, and human biology with the goal of showing how the elements are interrelated. More discussion on the key elements is provided below the diagram.

    Genetics, Epigenetics, and Human Biology genetics

     

    GENOME

    The human genome is the sum of the body's DNA and is considered to be static for each individual—remaining the same over a lifetime. The human genome contains all the instructions needed to make the full range of human cell types including muscle cells and neurons. This includes all of the body's DNA, both the genes (the coding regions) and the noncoding DNA, as well as the genetic material of the mitochondria and chloroplasts.

    With the breakthrough in gene testing now available, it is possible to isolate relevant genes from a field of  approximately 20,000 different genes. These 20,000 different genes make up less than 2% of the total amount of DNA.

    It has been found that the underlying gene patterns can exhibit "genetic variations". Ultimately, genetic variations are caused by variations in the order of bases in the nucleotides in genes. New technology, such as that used in the BodySync genetics test, allows scientists to directly sequence DNA which has identified even more genetic variation than was previously detected by previous methods such as protein electrophoresis.

    Examination of DNA has shown genetic variation in both coding regions and in the non-coding intron (nonprotein-coding sections) region of genes. Mutation is the ultimate source of genetic variation, but mechanisms such as sexual reproduction and genetic drift contribute to it as well.

    Genetic variation will result in phenotypic variation if variation in the order of nucleotides in the DNA sequence results in a difference in the order of amino acids in proteins coded by that DNA sequence, and if the resultant differences in amino acid sequence influence the shape, and thus the function of the enzyme.

    Genetic variations/base substitutions can change a codon to one that encodes a different amino acid and cause a small change in the protein produced. For example, sickle cell anemia is caused by a substitution in the beta-hemoglobin gene, which alters a single amino acid in the protein produced.

    Genetic variations can change a codon to one that encodes the same amino acid and causes no change in the protein produced. These are called silent mutations.

    Also, base substitutions can change an amino-acid-coding codon to a single "stop" codon and cause an incomplete protein. This can have serious effects since the incomplete protein probably won't function.

    In some genetic variations there may be a piece of the DNA deleted or inserted in a gene that may also lead to Present/Insertion or Deletion variation (INDEL). Since protein-coding DNA is divided into codons three bases long, insertions and deletions can alter a gene so that its message is no longer correctly parsed.

    When it comes to genetic traits, scientists look at genes and the locus where that gene or trait encodes on the chromosome. Since humans possess two copies of each chromosome, they also have two copies of each gene and locus on those chromosomes. Each of these trait-encoding genes (or loci) is called an allele. If the alleles match, the person is homozygous for that trait. If the alleles are different, the person is heterozygous for that trait.

    If a mutation occurs in just one copy of the gene then that individual is considered heterozygous. On the other hand if both copies of a gene are mutated then that individual is homozygous genotype. Many of these mutations can have undesirable health affects for an individual.

    BodySync's technology has helped to usher in the age of personalized nutrigenomics. The company has built its intellectual property and technology to support its vision of providing services in partnership with health care professionals (HP). BodySync's NutriSync (NS) genetics test consists of only the most well-researched genetic variations with direct applicability to actionable personalized health and wellness recommendations (most of which fall into the epigenetic category).

    The NutriSync genetics test has been based on evaluations of thousands of peer reviewed articles, published research papers, and human intervention studies, as well as extracting data of tens of thousands of DNA and self-reported lifestyle samples in its database.

    EPIGENOME

    The human epigenome serves as a bio-record of chemical changes that have occurred in a person's DNA and their histone proteins. Unlike the underlying genome which is largely static within an individual, the epigenome can be dynamically altered by environmental conditions. For example methyl groups from the diet can tag DNA and activate or repress certain genes as shown in the diagram below.

    The epigenome is involved in regulating gene expression, development, tissue differentiation, and suppression of transposable elements. These changes in underlying DNA and histone proteins can be passed down to an organism's offspring via transgenerational epigenetic inheritance. Changes to the epigenome can result in changes to the structure of chromatin and changes to the function of the genome.

    EPIGENETICS

    Epigenetics, on the other hand, is the study of changes in gene expression (active versus inactive genes) that do not involve changes to the underlying DNA sequence — a change in phenotype (the manifestation that is YOU) without a change in genotype — which in turn affects how cells read the genes. To be sure, epigenetic change is a regular and natural occurrence in our bodies, but can also be influenced by several factors including age, the environment/lifestyle, drug usage, and disease state.

    Epigenetic modifications can manifest as commonly as the manner in which cells terminally differentiate to end up as skin cells, liver cells, brain cells, etc. Also, epigenetic change can have more damaging effects that can result in diseases like cancer. At least three epigenetic mechanisms (two of which are shown in the diagram below) including DNA methylation, histone modification, and non-coding RNA (ncRNA)-associated gene silencing are currently considered to initiate and sustain epigenetic change.

    genetics epigenetics mechanisms

    ENVIRONMENT

    In this context the term "ENVIRONMENT" refers to all of the "external" influences we experience. In the diagram we list what are generally considered to be positive and negative factors contributing to our overall health.

    Some of these factors such as free-radicals and drug use affect our genome directly. Environmental agents such as UV light, ionizing radiation, and genotoxic chemicals (e.g. the drug thalidomide) can cause DNA damage. DNA damage is very frequent, occurring on average about 10,000 times a day per cell of the human body.

    These damages are largely repaired, but at the site of a DNA repair, epigenetic changes can remain. In particular, a double strand break in DNA can initiate unprogrammed epigenetic gene silencing both by causing DNA methylation, as well as by promoting silencing types of histone modification.

    The field of epigenetics is rapidly growing and with it the understanding that both the environment and individual lifestyle directly interact with the genome to influence changes in the way various genes are expressed. These changes may be reflected at various stages throughout a person’s life and even in later generations. For example, human epidemiological studies have provided evidence that prenatal and early postnatal environmental factors influence the adult risk of developing various chronic diseases and behavioral disorders.

    Also, research has also shown that a mother’s exposure to pollution could impact her child's asthma susceptibility and her intake of Vitamin D could change DNA methylation that influences placenta functioning. It doesn’t stop at the mother, however, as further studies support that the father has a hand in his child’s health and epigenetic marks, as well.

    Although our epigenetic marks are more stable during adulthood, they are still thought to be dynamic and modifiable by lifestyle choices and environmental influence. It is becoming more apparent that epigenetic effects occur not just in the womb, but over the full course of a human life span, and that epigenetic changes could be reversed. There are numerous examples of epigenetics that show how different lifestyle choices and environmental exposures can alter marks on top of DNA and play a role in determining health outcomes.

    The environment is being investigated as a powerful influence on epigenetic tags and disease susceptibility. Pollution has become a significant focus in this research area as scientists are finding that air pollution could alter methyl tags on DNA and increase one’s risk for neurodegenerative disease. Also, adequate amounts of B vitamins may protect against harmful epigenetic effects of pollution and may be able to combat the harmful effects that particulates have on the body.

    Diet has also been shown to modify epigenetic tags in significant ways. The field of nutriepigenomics explores how food and nutritional supplements and epigenetics work together to influence health and well being. For example, a study found that a high fat, low carbohydrate diet could open up chromatin and improve mental ability via HDAC (histone deacetylase) inhibitors.

    Other studies have found that certain compounds within the foods we consume could protect again cancer by adjusting methyl marks on oncogenes or tumor suppressor genes. Ultimately, an epigenetic diet may guide people toward the optimal food regimen as scientific studies reveal the underlying mechanisms and impact that different foods have on the epigenome and health.

    RNA/PROTEIN

    Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation, and expression of genes. RNA and DNA are nucleic acids, and, along with lipids, proteins and carbohydrates, constitute the four major macromolecules essential for all known forms of life.

    Like DNA, RNA is assembled as a chain of nucleotides, but unlike DNA it is more often found in nature as a single-strand folded onto itself, rather than a paired double-strand. Cellular organisms use messenger RNA (mRNA) to convey genetic information that directs synthesis of specific proteins.

    These protein molecules are the "workhorses" of the cell carrying out all the functions necessary for life. For example, enzymes, including those that metabolize nutrients and synthesize new cellular constituents, as well as DNA polymerases and other enzymes that make copies of DNA during cell division, are all proteins.

    PHENOTYPE

    Your phenotype is a description of your actual physical characteristics. This includes straightforward visible characteristics like your height and eye color, but also your overall health, your disease history, and even your behavior and general disposition. Do you gain weight easily? Are you anxious or calm? Do you like cats? These are all ways in which you present yourself to the world, and as such are considered phenotypes.

    However, not all phenotypes are a direct result of your genotype; chances are that your personal disposition to cats is the result of your life’s experience with pets (epigenetic) rather than a mutation in a hypothetical cat fancier gene.

    Most phenotypes are influenced by both your genotype and by the unique circumstances in which you have lived your life, including everything that has ever happened to you (epigenetic). We often refer to these two inputs as “nature,” the unique genome you carry, and “nurture,” the environment in which you have lived your life.

    HEALTH AND DISEASE

    Your phenotype expresses who YOU are in a multitude of ways and in particular shows your strengths and weaknesses regarding health, mental abilities, and athletic performance to name a few. By incorporating genetics and epigenetic tests and controlling your environment in positive ways your strengths can be expressed more easily and your weaknesses minimized!!

    CONCLUSION

    I have provided an overview of how genetics testing provides new scientific insights into many health issues that have previously not been well understood. An overview of genetics, epigenetic, and human biology has been provided that shows the overall relationships of these topics. Hopefully, the rationale is clear for adding genetic testing into programs that provide protocols for more successful healing regimens.

     

    ADDITIONAL RESOURCES

    HOMOCYSTEINE GENETICS – COENZYME B VITAMINS

    REJUVENATION PROGRAM SERIES

    Rejuvenation Program Part Ten: The Yoga Program

    Rejuvenation Program Part Nine: Acupuncture. Supporting Protocols Part Four – Acupuncture and Traditional Chinese Medicine (TCM).

    Rejuvenation Program Part Eight: Massage. Supporting Protocols Part Three – The Massage Program.

    Rejuvenation Program Part Seven. Supporting Protocols Part Two – The Magnesium Chloride Program

    Rejuvenation Program Part Six. Supporting Protocols Part One (garlic, hydrotherapy, and sauna therapy programs).

    Rejuvenation Program Part Five. Beyond foundational supplements. Seven enhancement supplements that supercharge your health. CoenzymeQ10 and/or Ubiquinol, Myo-Mag, Hepa Plus, Nascent Iodine, Echinacea, Immune-Assist™.

    Rejuvenation Program Part Four. The role of foundational supplements (multivitamin, Vitamin C / antioxidant formula, Rejuvenate!™ superfoods) for health.

    Rejuvenation Program Part Three. Health building nutrition and the role of dietary nucleic acids (RNA, DNA, nucleosides, and nucleotides).

    Rejuvenation Program Part Two. Foundational elements in the HPDI Rejuvenation Program: 1) Attitude/Commitment, 2) Detoxification, 3) Preventing Toxicity, 4) Health Building Nutrition, 5) Building Powerful Immunity, and 6) Supporting Protocols.

    Rejuvenation Program Part One. Introducing the HPDI Master Rejuvenation Program and its foundational elements. The importance of Attitude/Commitment.

     

  • REJUVENATE! PLUS SUPERFOOD — NEW IMPROVED FORMULA

    Fred Liers PhD rejuvenate! plus superfoodAs if Rejuvenate! PLUS weren't already the delicious, nutritious superfood you know and love. Now, Dr. Hank Liers, HPDI's formulator, has enhanced the formula for a truly remarkable taste and nutrition experience, you must try for yourself to believe!

    The name Rejuvenate! Plus remains, but think of it as "version 2.0" because the nutritional upgrades and taste improvements are striking.

    By the way, the "new" Rejuvenate! Plus is available now, so you can look forward to a truly remarkable user experience. We are confident you will be more than pleasantly surprised.

    You will not believe your tastebuds when you try the new Rejuvenate! Plus. My humble opinion? Dr. Hank (my father and HPDI's formulator) has knocked it out of the park in his revised formula.

    Reports from sample testers have been overwhelmingly positive! Individuals who loved Rejuvenate! Plus unanimously love the new formula even more. That says a lot about this reformulation.

    Rejuvenate! Plus sweet green superfood Rejuvenate! Plus 2.0 – healthy ingredients and taste at whole new level!

    Other testers, who preferred our Rejuvenate! Berries & Herbs or Original Greens formulas either say they will now add Rejuvenate! Plus to their regimen, or will mix it in with their current favorite Rejuvenate! superfood.

    Some individuals sampling the new formula who had never tried it before or previously did not often use Rejuvenate! Plus have decided to use it as their primary superfood—or take it daily.

    We couldn't be happier because these reports confirm the new Rejuvenate! Plus is a significant improvement over previous versions, and make our year-long effort to reformulate the product worth it. These early reports based on product samples show we have succeeded!

    Some things haven't changed: Rejuvenate! Plus remains the most popular and best-selling of all HPDI Rejuvenate superfoods. As always, it provide therapeutic levels (at least 340 mg) of dietary nucleic acids (RNA, DNA), greens (chlorella and spirulina) as in the lighter, sweeter greens (as compared to dark intense green-ness of Rejuvenate! Original greens) that both leads to slower, yet effective detoxification, and is powerfully energizing and cleansing. Rejuvenate! Plus also remains a foundational supplement that retains a complete built-in multivitamin sub-formula.

    What then has changed? In short, we have changed a few ingredients, added or upgraded other ingredients, increased protein and nucleic acids (RNA) content, and created better tasting product overall. Here is a brief summary:

    The "new" Rejuvenate! PLUS features (per serving):

    1) 500 mg more spirulina (1,900 mg total), which actually increases the RNA content by about 15 mg

    2) 2.3 grams more protein for a total of 13.9 grams

    3) Almost no sugar (just 0.6 g total)

    4) 2.3 g of powerful broccoli and alfalfa sprout extract powders

     5) 200 mg of organic BiAloe® aloe vera powder with over 18% acemannan

    6) 5-MTHF (500 mcg) — a better form of folate

    6) An extremely smooth texture, and even more delicious taste—users rate as significantly better than prior versions—which says a lot because Rejuvenate! Plus already tasted great.

    In short, these are the changes that make the new, improved Rejuvenate! Plus a significantly better product. Now I will delve a bit deeper into each of these changes, as well as specific changes to ingredients.

    Rejuvenate! Plus superfood The new Rejuvenate! PLUS offers major improvements for optimal health.

    REJUVENATE! PLUS IS A UNIQUE, HIGH-RNA SUPERFOOD

    Rejuvenate! Plus is one three high-RNA superfoods Hank Liers of HPDI intentionally formulated to provide therapeutic levels of dietary nucleic acids. In this case, that means about 340 mg of nucleic acids per serving, and that has now been increased to at least 355 mg. The fact that Rejuvenate! Plus provides such high levels of dietary nucleic acids makes it—and the entire line of Rejuvenate! superfoods—unique!

    A short history lesson: Benjamin S. Frank, MD, PhD discovered the benefits of dietary nucleic acids in the 1960s and 1970s. He performed various studies on humans and animals using various intakes of dietary RNA. He concluded that nucleic acids are essential nutrients like vitamins and minerals. Nucleic acids provide a host of unique health benefits that make getting RNA in your diet important.

    After reading of Dr. Benjamin S. Frank's works (including Dietary Nucleic Acid Nutrition and Therapy and The No-Aging Diet), my father Hank Liers and I decided to formulate a line of superfoods based on the idea of providing high levels of dietary nucleic acids for optimal health. That was 10 years ago.

    Rejuvenate! Original Greens launched in 2007. Rejuvenate! Plus came two years later in 2009. Then Rejuvenate! Berries & Herbs in 2010. To this day, no other company has created dedicated high-RNA superfoods like HPDI's Rejuvenate line.

    DIETARY NUCLEIC ACIDS IN REJUVENATE! PLUS

    What makes Rejuvenate! PLUS—and in fact the entire Rejuvenate! line of superfoods—unique? A single serving provides therapeutic levels (340+ mg) of dietary nucleic acids (RNA, DNA, nucleotides, and nucleosides). Here are a few of the benefits and effects of nucleic acids in the body:

    • HIGHER ENERGY (ATP) PRODUCTION
    • GREATER MUSCLE MASS / STRENGTH / ENDURANCE
    • SMOOTHER SKIN / MORE YOUTHFUL APPEARANCE
    • EASIER BREATHING / “ANTI-ANOXIA” EFFECT
    • ELEVATES TISSUE OXYGENATION
    • BENEFICIAL CARDIOVASCULAR EFFECTS
    • LOWER CHOLESTEROL LEVELS
    • OVERALL PHYSICAL REJUVENATION
    • TEMPERATURE TOLERANCE (COLD/HEAT)
    • IMPROVES LONGEVITY / QUALITY OF LIFE
    • FAR GREATER SUBJECTIVE WELL-BEING

    Source: Nucleic Acid Nutrition and Therapy

    Nucleic acids perform so many important functions in the body that getting sufficient amounts in the your diet is probably essential, just as Dr. Benjamin S. Frank asserts. That can be difficult since historically they were obtained from fish, organ meats—foods that people today may not consume in sufficiently high amounts for a variety of reasons. These reasons may include issues of taste, emphasis on vegetarian foods, concern about heavy metals or radiation, or lack of availability.

    Rejuvenate! Plus in many ways helps take the guesswork from obtaining "essential" dietary nucleic acids by providing a vegetarian, gluten free, and non-GMO source of dietary RNA—along with protein, vitamins, minerals, cofactors, and other important nutrients—in a tasty, easy-to-take powder that stays fresh for months, travels well, and can be taken in a variety of ways from smoothies to plain water!

    TRY REJUVENATE! PLUS

    You (or your clients) have everything to gain by trying Rejuvenate! PLUS. As you can see, the updated superfood is carefully formulated to help create and maintain optimal health.

    When used together with other HPDI foundational supplements and the HPDI supplement system, Rejuvenate! Plus is another "brick in your wall" of good health and can make a huge difference in terms of how you feel, perform, and function in life.

    Try the new, improved Rejuvenate! PLUS "2.0" superfood. See for yourself not only how good it tastes, but how good it can help make you feel. That's goodness all around!

    RESOURCES

    Articles

    Nine Things to Know About Rejuvenate Superfoods

    Dietary Nucleic Acids – Dr. Benjamin S. Frank, Part 1

    Dietary Nucleic Acids – Dr. Benjamin S. Frank, Part 2

    Super-Tasty Morning Nutritional Drinks

    Product Reviews

    Rejuvenate! PLUS Superfood is High in DNA and RNA with sprouts, chlorella & more by Mike Adams

    Product Review: Rejuvenate Berries & Herbs superfood is rich in RNA, plant proteins by Mike Adams

    Superfood for Cellular Survival by Dr. Mark Sircus

    Books

    Nucleic Acid Nutrition and Therapy by Benjamin S. Frank, MD, PhD

    Dr. Frank's No-Aging Diet: Eat and Grow Younger by Benjamin S. Frank, MD, PhD

    Nucleic Acid and Anti Oxidant Therapy of Aging and Degeneration by Benjamin S. Frank, MD, PhD

    Nucleic Acid Therapy in Aging and Degenerative Disease–A Metabolic Approach with DNA, RNA, and Related Metabolites by Benjamin S. Frank, MD, PhD

    Rejuvenate! Superfoods

    Rejuvenate! Superfoods

    Rejuvenate! comparison page

    Rejuvenate! PLUS

    Rejuvenate Berries & Herbs

    Rejuvenate! Original Greens

    Videos

  • THE TRUTH ABOUT ESSENTIAL FATTY ACIDS

    The Truth About Essential Fatty Acids

    Dr. Hank Liers, PhD essential fatty acidsMany in the field of nutrition have lost sight of the fact that there are two essential fatty acids needed by the body. Many people recommend omega-3 fatty acids assuming the the body gets sufficient omega-6 from the diet. The truth about essential fatty acids is more complicated. This article will show the more complete and correct picture.

    BACKGROUND

    Fatty acids are part of the lipids class, widely found in nature, food, and organisms. These fatty acids are a critical constituent of the cell membranes in all of the trillions of cells in the body. They have important biological functions including structural, communication, and metabolic roles, and they represent an important source of energy. Their metabolism produces a huge quantity of adenosine triphosphate (ATP). The beta-oxidation of the fatty acids is a well-known process, mostly used by the heart and the muscular tissue to obtain energy.

    Figure 1 below shows a schematic diagram of what a fatty acid looks like. One end of the structure in all cases has a carboxylic acid group (COOH) and the other end in all cases has a methyl group (CH3). Saturated fats have single bonds (-) between all carbon atoms (C), but unsaturated fats have a number of double bonds (=) between some of the carbon atoms.


    essential fatty acids Figure 1 - Basic diagram of fatty acids structure

    The human body can synthesize many of these fatty acids, except the essential fatty acids (PUFAs) linoleic acid (LA) and alpha-linolenic acid (ALA). These two are generally found in various vegetable oils, but their important metabolites are found mainly in special vegetable oils such as borage oil and in fish oils. Linoleic acid is the most abundant fatty acid in nature, and it is the precursor of other omega-6 fatty acids. Omega-3 fatty acids are synthesized from alpha-linolenic acid.

    Once ingested, short-chain PUFAs are converted to long-chain fatty acids. These are critical for mammalian cells in order to perform various biological functions, such as sustaining the structural integrity of cellular membranes and serving as signaling molecules. They are highly enriched in brain tissues, where they participate in the development and maintenance of the central nervous system during both embryonic and adult stages.

    Polyunsaturated fatty acids have been extensively researched. They include the essential fatty acids linoleic acid (an omega-6) and alpha linolenic acid (an omega-3). Omega-3s are not abundant in our food chain. There is none in corn oil and very little in soy oil, the two most widely used food oils. Therefore, nearly all the early research with polyunsaturated oils utilized omega-6 fatty acids, predominantly as linoleic acid.

    Fish oils were neglected out of ignorance or because the investigators chose to pass over these cholesterol-containing oils. Concern eventually developed over the close association between increasing incidence of mammary tumors and high intake of omega-6 polyunsaturated fatty acids. After some years, researchers finally turned their investigations to the interrelationship between dietary omega-6 and omega-3 fatty acids.

    FATTY ACID METABOLIC PATHWAYS

    The following diagram shows in detail the pathways for the production and use of fatty acids in the body. In the figure the metabolic pathways (running left to right) for four fatty acids types are shown (top - Omega-3, second - Omega-6, third - Omega-9, bottom - Omega-7). Notice that only the omega-3 and omega-6 oils are considered to be essential fatty acids because they cannot be made in the body. This means they must come from food.

    essential fatty acids Figure 2 - fatty acid metabolism pathways in the body

    The diagram shows a series of enzyme induced reactions that either add a double bond or two additional carbon/hydrogen pairs to the fatty acid. The enzymes that make this happen are called desaturase and elongase. The desaturase enzymes are given a number for the carbon number (that the enzyme is working on) from the methyl end of the fat. These same enzymes work on all of the fatty acid types. For example, Delta 6 desaturase causes an additional double bond to be inserted into both alpha-linolenic (omega-3) and linoleic acid (omega-6) (as well as oleic acid and palmitoleic acids).

    In this way, the body is able to produce a wide variety of fatty acids that have their own unique effects on biochemistry. Some of these are more important than others. In particular, the omega-3 essential fatty acid eicosapentanoic acid (EPA), the omega-6 essential fatty acid dihomo-gamma-linolenic acid (DGLA), and the omega-6 essential fatty acid arachidonic acid (AA) are precursors for a class of chemicals called eicosanoids/prostaglandins that have far reaching affects on key body functions.

    EICOSANOIDS/PROSTAGLANDINS

    Eicosanoids are prostaglandins that affect many aspects of health both positively and, in some cases, negatively. All known eicosanoids and prostaglandins are formed from the essential fatty acids linoleic acid (omega-6, or n-6), alpha linolenic acid (omega-3, or n-3), their "enhanced" derivatives, and from the omega-3 fatty acids in fish oils.

    Prostaglandins are short-lived highly active, hormone-like chemicals that are found in every cell of the body. They are regulators of cell activity and essential for maintaining health. Each cell type or organ produces its own form of prostaglandin to carry out its functions. There are three types of prostaglandins: PG1, PG2, and PG3.

    Series 1 Prostaglandins (PG1), derived from gamma-linolenic acid (GLA), the active component of borage oil, has many beneficial effects: It makes platelets less sticky, lowers blood pressure by relaxing smooth muscles in the walls of arteries, increases loss of sodium and water, decreases inflammation and enhances immunity.

    Series 2 Prostaglandins (PG2), also derived from GLA, is used in "fight or flight" (stress) situations, - the fight against danger, or the flight from it. In modern lifestyles which are high in stress but low in physical activity, continuous production of Series Two Prostaglandins results in sticky platelets, high blood pressure, increased water and sodium retention, increased inflammation and decreased immune system capabilities.

    Series 3 Prostaglandins (PG3), derived from eicosapentaenoic acid (EPA), the active component of fish oil, has beneficial effects. They block the detrimental effect of the Series 2 Prostaglandins, preventing them from being made in the body. As a result the platelets are less sticky, blood pressure is lower because the muscles in the walls of our arteries remain relaxed, loss of sodium and water by the kidneys takes place more effectively, inflammation response is decreased, and immune function is efficient.

    It is now known that the ratios of these dietary fatty acids are very important. Consumption of linoleic acid leads to production of the enhanced fatty acid, arachidonic acid (20:4n-6). Prostaglandins based on arachidonic acid exacerbate stress and inflammatory states, and suppress immunoprotective functions (i.e. resistance to disease). Too much linolenic acid and other omega-3s may cause excessive bleeding during injury, surgery, or childbirth. Large amounts of any of these unsaturated fatty acids in the diet without a compensatory increase in antioxidant nutrients (especially Vitamin E), can speed oxidative damage to tissues, resulting in accelerated aging while increasing the risk of degenerative diseases.

    Yet, a balanced ratio of both omega-3 and omega-6 fatty acids in the diet offers very positive health benefits. When omega-3 fatty acids predominate, the body will produce less arachidonic acid (20:4n-6). Immunity improves and inflammation subsides.

    Essential Fats

    Unfortunately, our Western diet has been almost devoid of omega-3 fatty acids. Creating the optimum intake of omega 3-to-omega 6 unsaturated fatty acids has become, therefore, an issue of prime importance for anyone concerned with health. We need to evaluate carefully the amounts of linoleic acid (n-6) we consume relative to our intake of alpha-linolenic acid (18:3n-3) and fish oils (EPA:20:5n-3 and DHA:22:6n-3).

    ESSENTIAL FATTY ACIDS - PATHWAYS

    The diagram in Figure 3 shows details of the omega-6 and omega-3 pathways. Pathway specifics indicate key eicosanoids (series 1 prostaglandins, series 2 prostaglandins, and series 3 prostaglandins), oil sources, and important nutrient cofactors that are needed for the reactions to take place.

    essential fatty acids Figure 3 - Essential Fatty Acids – pathways in the body

    The information is this diagram gives the clues we need in order to provide optimal types and amounts of omega-6 and omega-3. For example, I have chosen for my essential fatty acid product cold pressed borage oil as the best natural source of gamma linoleic acid (GLA). It contains 20% by weight — the highest amount found in natural oils.

    RESEARCH ON ESSENTIAL FATTY ACIDS

    Work by Chapkin et. al. (see references 1–4 below) has identified the potent synergistic relationship between GLA, an omega-6 fatty acid, and the well-known omega-3 fatty acids. Chapkin has shown that, rather than simply the quantity of dietary omega-3s, it is the ratio of omega-6 to omega-3 fatty acids that is important in achieving full cardiovascular health and inflammatory control.

    Furthermore, Chapkin has identified the ideal ratio. His published work deals with the importance of mixed diets supplying both linoleic and linolenic acids. To underscore the importance of these two fatty acids, refined oil supplements rich in enhanced forms were used. "Enhanced forms" are fatty acids derived from the original. They are one or more steps closer to the actual eicosanoid. In the human body, alpha linolenic acid (18:3n-3) is eventually converted to eicosapentaenoic acid (EPA, 20:5n-3) and linoleic acid (18:2n-6) is converted to gamma-linolenic (GLA, 18:3n-6) as its first enhanced form. Both enhanced fatty acids are precursors to eicosanoids.

    In Chapkin's research, superior health benefits were delivered by the mixed diet that supplied the eicosanoid precursors in a specific ratio. The balanced ratio of enhanced Omega-6 (GLA)-to-Omega-3 (EPA) fatty acids was 1:4.

    IMPLEMENTATION OF THE SCIENCE

    Based upon the science discussed above, I developed a product with the correct Omega-6 (GLA)-to-Omega-3 (EPA) ratio and with proper amounts. It is available to you as Hank & Brians Essential Fats Plus E from Health Products Distributors, Inc. (HPDI).

    Essential Fats Plus E

    ESSENTIAL FATS PLUS E IS A HIGHLY ADVANCED ESSENTIAL FATTY ACIDS SUPPLEMENT
    OFFERING SPECIAL BENEFITS:

    1. UNIQUE COMBINATION — Essential Fats (EPA, DHA, GLA) plus Vitamin E. This unique formula offers more than one type of Vitamin E (not just d-alpha-tocopherol) and balanced essential fats.
    2. BALANCED ESSENTIAL FATS— Many EFA supplements contain only omega-3s, but for optimal function the body requires a balance of omega-3 and omega-6 essential fats. In addition, our special formula provides a 4-to-1 ratio of EPA to GLA in order to achieve a balance you need for optimal health.
    3. FULL-SPECTRUM VITAMIN E — Tocotrienols and tocopherols in this formula are natural vitamin E substances derived from oryza rice bran oil and protect polyunsatured EFAs against free-radical damage both in the capsule and in your body. Many Vitamin E supplements contain only d-alpha tocopherol, which is only a single component of the full-spectrum Vitamin E in this formula.
    4. ULTRAPURE — Molecularly distilled oils of extremely high-purity containing no PCBs, heavy metals, or oxidized contaminants. Free of excipients, additives, and common food allergens!

    COMPOSITION: Six softgel capsules provides the following percentages of the Daily Value.

    NUTRIENT AMOUNT % Daily Value†
    EPA (Eicosapentaenoic Acid 20:5 omega 3)
    (from 2,000 mg of purified fish oils)
    360 mg *
    DHA (docosahexaenoic Acid 22:6 omega 3)
    (from 2,000 mg of purified fish oils)
    240 mg *
    GLA (Gamma Linolenic Acid 18:3 omega 6)
    (from 450 mg of cold pressed borage seed oil)
    90 mg *
    Vitamin E (d-alpha-tocopherol) (from 180 mg of Oryza rice bran oil) 24 IU 81%
    Mixed Tocotrienols (d-gamma, d-alpha, and d-delta)
    (from 180 mg of Oryza rice bran oil)
    28.8 mg *

    * No established Daily Value
    † Daily Values based on a 2,000 calorie diet

    IMPORTANT FUNCTIONS OF ESSENTIAL FATTY ACIDS

    Below we provide some of the functions and benefits obtained when by diet or supplementation the correct ratios and amounts of essential fatty acids are consumed.

    • Regulate steroid production and hormone synthesis
    • Regulate pressure in the eyes, joints, and blood vessels
    • Regulate response to pain, inflammation, and swelling
    • Mediate Immune Response
    • Regulate bodily secretions and their viscosity
    • Dilate or constrict blood vessels
    • Regulate smooth muscle and autonomic reflexes
    • Are primary constituents of cellular membranes
    • Regulate the rate at which cells divide
    • Necessary for the transport of oxygen from the red blood cells to tissues
    • Necessary for proper kidney function and fluid balance
    • Prevent red blood cells from clumping together
    • Regulate nerve transmission

    GENETIC TESTING AND ESSENTIAL FATTY ACIDS

    Please note that genetic testing for a wide range of genes and the enzymes they produce has indicated that essential fatty acids can be an important factor in helping the body overcome a variety negative gene variations. These negative gene variations include genes that relate to: 1) Inflammatory Response, 2) Exercise Performance, 3) Exercise Recovery, 4) Cardiovascular Fitness, 5) Body Composition, and 6) VO2 Max, Aerobic Capacity.

    We will discuss this more deeply in a future blog article.

    CONCLUSION

    The body is best protected from a range of health issues when we supply a mixed diet of both omega-3 and omega-6 essential fatty acids. Studies show that we do not need to consume large amounts of fatty acids if the ratio is correct. These findings indicate that, for a typical human body, amounts of 90 mg GLA (18:3n-6) to 360 mg EPA (20:5n-3) taken daily will provide for the optimum production of the three major prostaglandins. These amounts are found in Hank & Brians Essential Fats Plus E.

    REFERENCES

    The following includes abstracts of Chapkin's published research on essential fatty acids.

    REFERENCE 1

    Chapkin RS Somers SD Erickson KL

    Dietary manipulation of macrophage phospholipid classes: selective increase of dihomogammalinolenic acid.

    In: Lipids (1988 Aug) 23(8):766-70

    Because alterations in the dietary content of fatty acids are an important method for modulating macrophage eicosanoid production, we have quantitated the levels of n-6 and n-3 polyunsaturated fatty acids in peritoneal macrophage individual phospholipids from mice fed diets (3 wk) with either safflower oil (SAF), predominantly containing 18:2n-6, borage, (BOR) containing 18:2n-6 and 18:3n-6, fish (MFO) containing 20:5n-3 and 22:6n-3, and borage/fish mixture (MIX) containing 18:2n-6, 18:3n-6, 20:5n-3 and 22:6n-3. Dietary n-3 fatty acids were readily incorporated into macrophage phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylserine (PS) and phosphatidylinositol (PI). The increase in n-3 fatty acid levels was accompanied by a decrease in the absolute levels of 18:2n-6, 20:4n-6 and 22:4n-6 in PC, PE and PS. Interestingly, PI 20:4n-6 levels were not significantly lowered (P greater than 0.05) in MIX and MFO macrophages relative to SAF and BOR. These data demonstrate the unique ability of this phospholipid to selectively maintain its 20:4n-6 levels. In BOR and MIX animals, 20:3n-6 levels were significantly increased (P less than 0.05) in all phospholipids relative to SAF and MFO. The combination of borage and fish oils (MIX diet) produced the highest 20:3n-6/20:4n-6 ratio in all phospholipids. These data show that the macrophage eicosanoid precursor levels of 20:3n-6, 20:4n-6 and n-3 acids can be selectively manipulated through the use of specific dietary regimens. This is noteworthy because an increase in phospholipid levels of 20:3n-6 and 20:5n-3, while concomitantly reducing 20:4n-6, may have therapeutic potential in treating inflammatory disorders.

    Institutional address: Department of Human Anatomy School of Medicine University of California Davis 95616.

     

    REFERENCE 2

    Chapkin RS Carmichael SL

    Effects of dietary n-3 and n-6 polyunsaturated fatty acids on macrophage phospholipid classes and subclasses.

    In: Lipids (1990 Dec) 25(12):827-34

    This study examined the effects of n-3 and n-6 polyunsaturated fatty acid alimentation on murine peritoneal macrophage phospholipids. Mice were fed complete diets supplemented with either corn oil predominantly containing 18:2n-6, borage oil containing 18:2n-6 and 18:3n-6, fish/corn oil mixture containing 18:2n-6, 20:5n-3 and 22:6n-3, or fish/borage oil mixture containing 18:2n-6, 18:3n-6, 20:5n-3 and 22:6n-3. After two weeks, the fatty acid levels of glycerophosphoserines (GPS), glycerophosphoinositols (GPI), sphingomyelin (SPH), and of the glycerophosphocholine (GPC) and glycerophosphoethanolamine (GPE) phospholipid subclasses were determined. We found that mouse peritoneal macrophage GPC contain primarily 1-O-alkyl-2-acyl (range for the dietary groups, 24.6-30.5 mol %) and 1,2-diacyl (63.2-67.2 mol %), and that GPE contains 1-O- alk-1'-enyl-2-acyl (40.9-47.4 mol %) and 1,2-diacyl (44.2-51.2 mol %) subclasses. In general, fish oil feeding increased macrophage 20:5n-3, 22:5n-3 and 22:6n-3 levels while simultaneously reducing 20:4n-6 in GPS, GPI, GPE and GPC subclasses except for 1-O-alk-1'-enyl-2-acyl GPC. Administration of 18:3n-6 rich diets (borage and fish/borage mixture) resulted in the accumulation of 20:3n-6 (2-carbon elongation product of 18:3n-6) in most phospholipids. In general, the novel combination of dietary 18:3n-6 and n-3 PUFA produced the highest 20:3n-6/20:4n-6 phospholipid fatty acid ratios. This study demonstrates that marked differences in the responses of macrophage phospholipid classes and subclasses exist following dietary manipulation.

     

    REFERENCE 3

    Fan YY Chapkin RS

    Mouse peritoneal macrophage prostaglandin E1 synthesis is altered by dietary gamma-linolenic acid.

    In: J Nutr (1992 Aug) 122(8):1600-6

    The ability of dietary gamma-linolenic acid [18:3(n-6)] to modulate prostaglandin biosynthesis in mouse resident peritoneal macrophages was determined. Mice were fed diets containing corn oil, borage oil or evening primrose oil or a mixture of borage and fish oils. After 2 wk, resident peritoneal macrophages were isolated and stimulated with unopsonized zymosan to induce prostaglandin synthesis. Borage oil, primrose oil and fish-borage oil mixture dietary groups (containing 25.6, 11.9 and 19.5 g gamma-linolenic acid/100 g fatty acids, respectively) had significantly (P less than 0.05) enhanced prostaglandin E1 synthesis (39.7, 29.4 and 73.0 nmol prostaglandin E1/mg protein, respectively) compared with corn oil-fed (containing less than 0.1 g gamma-linolenic acid/100 g fatty acids) animals, which synthesized less than 0.1 nmol prostaglandin E1/mg protein. Borage oil- and fish-borage oil mixture-fed mice had the highest biosynthetic ratio of prostaglandin E1/prostaglandin E2 (E1/E2 approximately 0.2). Macrophages from borage oil-fed mice synthesized the lowest amount of prostacyclin (198.7 nmol 6-keto-prostaglandin F1 alpha/mg protein) compared with corn oil-, primrose oil- and fish- borage oil mixture-fed mice (379.7, 764.8 and 384.2 nmol 6-keto- prostaglandin F1 alpha/mg protein, respectively). In addition, borage oil-, primrose oil- and fish-borage oil mixture-fed mice had significantly (P less than 0.05) higher levels of dihomo-gamma- linolenic acid [20:3(n-6)] in membrane phospholipids (5.5, 3.5 and 5.7 mol/100 mol, respectively) relative to corn oil-fed mice (2.0 mol/100 mol).

     

    REFERENCE 4

    Fan YY Chapkin RS Ramos KS

    Dietary lipid source alters murine macrophage/vascular smooth muscle cell interactions in vitro.

    In: J Nutr (1996 Sep) 126(9):2083-8

    This study was conducted to compare the impact of dietary lipids on the ability of macrophages to modulate vascular smooth muscle cell (SMC) DNA synthesis in vitro. C57BL/6 female mice were fed six different diets (6 mice/diet) containing 10% fat from corn oil (CO), borage oil (BO), primrose oil (PO), fish-corn oil mix (FC, 9:1, w/w), fish-borage oil mix (FB, 1:3, w/w), or fish-primrose oil mix (FP, 1:3, w/w) for 2 wk. Peritoneal macrophages were isolated from these mice, stimulated with zymosan or vehicle, and subsequently co-cultured with naive mouse aortic SMC in the presence of 3H-thymidine to measure SMC DNA synthesis. In this co-culture system, macrophages were seeded on 25-mm culture inserts (upper chamber) and SMC were seeded on 35-mm culture dishes (lower chamber). The two cell types were separated by a semipermeable membrane with a 30-kD cut-off. When quiescent SMC were co-cultured with macrophages, only the PO and FP diet groups had significantly (P < 0.05) lower SMC DNA synthesis compared with the control CO group whose diet contained no gamma- linolenic acid (GLA) or (n-3) polyunsaturated fatty acids (PUFA). In contrast, when cycling SMC were co-cultured with diet-modulated macrophages, all dietary groups except for those fed FC had significantly lower (P < 0.05) SMC DNA synthesis relative to the CO group. Although the level of GLA in PO and BO diets was different (11.5 and 22.3 g/100 g fatty acids, respectively), these treatments exerted comparable inhibitory effects on SMC DNA synthesis. The FP treatment consistently exhibited the lowest SMC DNA synthetic profile among the six dietary groups irrespective of SMC growth conditions. These data suggest that BO and PO alone or in combination with fish oil influence macrophage/smooth muscle cell interactions in a manner consistent with favorable modulation of the atherogenic process.

    These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

    BOOKS

    1. Enig, Mary G. Know Your Fats: The Complete Primer for Understanding the Nutrition of Fats, Oils, and Cholesterol. Bethesda Press, 2000.
  • BONE FRACTURES SUPPORT

    Dr. Hank Liers, PhD bone fracturesSeveral years ago a customer asked me for a program that could be helpful to those suffering with bone fractures. A relative had been diagnosed with multiple bone fractures in his ankle.

    Since I have been counseling individuals regarding natural treatments for supporting those with bone fractures and injury for many years, and was able to provide a comprehensive program that could be helpful in recovery. More recently, we have introduced products and tools that can be even more supportive. Therefore, in this article we are providing an update to the bone fractures program.

    Clearly, the need for such a program is great. According to the American Academy of Orthopaedic Surgeons (AAOS), about six million individuals suffer fractures each year in North America. In about 5–10 percent of cases, patients suffer either delayed healing or fractures that do not heal.

    The problem of bone fractures is especially troubling for the elderly, many of whom suffer from osteoporosis, a condition in which bones become weak and break more easily. For an older person, a fracture affects quality of life because it significantly reduces function and mobility, and requires an extended period of recuperation.

    The bone fracture program set forth below also works well to support the healing of other types of bone problems, including broken bones, bone surgery, osteoporosis, and wisdom tooth removal.

    THE BONE FRACTURE PROGRAM

    IMPORTANCE OF FOUNDATIONAL SUPPLEMENTS

    The first element of the program consists of Foundational Supplements. This group of supplements ensures the body is being supplied with all of the basic elements needed for optimal function. The primary foundational supplements consists of 1) a therapeutic multivitamin and mineral formula, 2) a complete buffered Vitamin C with antioxidants formula, 3) an essential fatty acids supplement, and 4) a high-RNA superfoods formula.

    Our Foundational Supplements are described in great detail on the HPDI website where we provide a free downloadable e-book "The Need for Foundational Supplements" (.pdf). Suffice it to say that the foundational supplements are a essential part of the program that ensure healing will take place quickly and effectively. I encourage everyone to become familiar with this information as foundational supplements are basic to any wellness or healing program.

    bone fractures

    ENHANCEMENT FORMULAS ARE CRITICAL FOR HEALING BONE FRACTURES

    The second element of the program for healing bone fractures consists of Enhancement Formulas that strengthen the body as it relates to dealing with the damaging effects of bone fractures. These include a Vitamin D3 formula with the synergistic nutrients of Vitamin A and Vitamin K2 that are required for the rebuilding of bone as well as strengthening the body in many other ways. The HPDI Vitamin D3 Plus formula to designed to specifically address this need.

    A second Enhancement Formula in this program is our comprehensive Bone Guardian formula that is based upon micronized veal bone that provides hydroxyapatite (Ca10(PO4)6(OH)2). Hydroxyapatite is the basic component of human bone that is 50% by volume and 70% by weight. Whereas the Vitamin D3 Plus formula builds the bone matrix, the Bone Guardian fills in the matrix with materials such as calcium, phosphorus, magnesium, boron, zinc, manganese, copper, silica, and strontium. HPDI sells Bone Guardian in both the tablet and capsule forms. The capsule form may be better for older people who are able to absorb capsules better than tablets.

    A third Enhancement Formula to the program is additional amounts of Vitamin C. Vitamin C is known to participate in every step of the process of building collagen, which is a key component of bone. Vitamin C has been shown to increase bone mass density. We recommend slowly increasing your intake of buffered Vitamin C until you reach your bowel tolerance. This can be accomplished by increasing your intake of HPDI's foundational supplement PRO-C™ formula. The PRO-C has the added value of containing oligomeric proanthocyanidins (OPCs) from grape seed, skin, & pulp. OPCs in the body are able to strongly crosslink and strengthen new and damaged collagen fibers needed needed to repair bones, ligaments, tendons, and cartilage.

    SPECIFIC CONDITION FORMULAS TARGET BONE FRACTURES

    The third element in the program are Specific Condition Formulas that directly address issues related to bone fractures. The first of these is the addition of a joint formula that allows the body to build and repair connective tissue and to significantly reduce inflammation in the area of bone fractures. In most cases of fractures there will be damaged ligaments and tendons as well as inflammation in the area.

    HPDI's Joint Health Formula includes the ingredients glucosamine hydrochloride, MSM, and sea cucumber (a significant source of chondroiten sulfate) in addition to anti-inflammatory substances such as turmeric extract, rutin, and grape extract (seed, pulp, and skin) that have been extremely helpful in both repairing connective tissue and reducing pain and inflammation.

    A second strongly recommended condition-specific formula is proteolytic enzymes. Because it is highly likely in the case of bone fractures and injury that there is significant tissue damage, a formula with pancreatic and plant enzymes as well as anti-inflammatories can be extremely helpful is clearing out the damaged tissue. This gives the body the opportunity to begin the rebuilding process much sooner.

    Our recommended PROLYT formula contains the proteolytic enzymes bromelain, trypsin (pancreatic enzyme), and chymotrypsin (pancreatic enzyme), and the polyphenols/bioflavonoids turmeric extract (95% curcuminoids), quercetin and oligomeric proanthocyanidins (OPCs) from grape extract. This formula when taken on an empty stomach between meals is quickly absorbed into the bloodstream and goes to work cleaning up any damaged tissues in the area surrounding a fracture and assists in reducing pain and inflammation.

    TOPICAL MAGNESIUM CHLORIDE FOR PAIN AND RAPID HEALING

    A final Specific Condition Formula that I highly recommend for healing bone fractures is to rub Ancient Minerals Magnesium Oil on and surrounding the fracture area. Bones cannot heal without having adequate amounts of magnesium available. Unfortunately, many people are deficient in magnesium and even taking oral magnesium cannot easily provide sufficient amounts to an area with a bone fracture. Magnesium oil (mostly magnesium chloride) is quickly absorbed transdermally (via skin) and often can provide rapid healing and pain relief!

    BODY pH COULD BE A FACTOR IN HEALING BONE FRACTURES

    The processed food diets with a high protein and low vegetable content consumed by many people in the U.S. and elsewhere often produce conditions in the body of acidity. This in turn leads to decreased oxygenation of cells and encourages a greater amount of anaerobic processes in metabolism. In addition, when the body is acidic calcium can be taken from bones in order to balance the acidity. This can lead to poor healing of bone fractures.

    In order to counter acidic conditions in the body we recommend the use of HPDI's pH ADJUST formula. As a dietary supplement, take 1 gm (about a rounded ¼ tsp) in 4-8 ounces of purified water preferably away from food, or as directed by a health care professional.  For extremely acidic conditions, try 4–10 doses per day, depending on acidity level. Use pH paper to ensure pH levels remain balanced, and do not become too alkaline (alkalosis may occur above pH 8.2).

    TESTING pH LEVELS: The best way to test pH levels is to use litmus paper, which HPDI offers in rolls (Hydrion brand) for this purpose. You can test salivary or urinary pH. In order to test salivary pH, simply use a small strip of pH paper to dip into a small amount of saliva. Advantages of pH paper include rapid results, ease of use, and cost effectiveness.

    pH Paper bone fractures protocol

    The color of the litmus paper indicates the pH level of the body fluid tested. Most litmus paper comes with an indicator chart showing colors corresponding to various pH levels. Alkaline states will generally produce a dark green, blue or purple color (most basic). Acidic states will range from yellow (most acidic) to light green.

    Salivary pH and urinary pH are significantly affected by recent food consumption and other factors, so it it best to test pH hours after meals or in the morning when you awake. We prefer to measure urinary pH since results are more consistent. Measuring urinary pH is a simple as placing a few drops of urine on the paper or dipping the paper into a sample cup of fresh urine.

    A consistent pH measurement of less than 7.0 indicates that you are too acidic (values less than 6.2 show extreme acidity). This indicates that you should consume more alkaline forming foods (usually vegetables) and/or take pH ADJUST. A single dose of pH ADJUST can change conditions in the body from acidic to alkaline within a few hours.

    GENETIC VARIATIONS IN YOUR VITAMIN D RECEPTOR GENE (VDR) MAY BE AN IMPORTANT FACTOR

    The VDR gene (contained in every cell of the body) provides instructions for making a protein called vitamin D receptor (VDR), which allows the body to respond appropriately to vitamin D. This vitamin can be acquired from foods in the diet or made in the body by exposure to from sunlight. Vitamin D is involved in maintaining the proper balance of several minerals in the body, including calcium and phosphate, which are essential for the normal formation of bones and teeth. One of vitamin D's major roles is to control the absorption of calcium and phosphate from the intestines into the bloodstream. Vitamin D is also involved in several process unrelated to bone formation.

    VDR attaches (binds) to the active form of vitamin D, known as calcitriol. Calcitrol is produced in the body from Vitamin D3 (cholecalciferol) in the liver and kidneys. The interaction with calcitriol allows VDR to partner with another protein called retinoid X receptor (RXR). The resulting complex of proteins then binds to particular regions of DNA, known as vitamin D response elements, and regulates the activity of vitamin D-responsive genes. By turning these genes on or off, VDR helps control calcium and phosphate absorption and other processes.

    In recent years, genetic tests have become available that show VDR variations can cause serious conditions related to low bone density and other important body functions such a higher blood glucose levels or lower immune system function. If a person is having little success in healing bone fractures, it is possible that VDR variations are a key factor of causation.

    In such cases, we recommend having genetic testing done to determine if VDR variations are present. Recently, HPDI has teamed with a genetic testing company (BodySync, Inc.) and sells the BodySync test kits on our Reseller site. Among the genes tested for in the test are three variations of the VDR gene. Resellers can purchase the test kits directly from HPDI and retail customers can call us  (800-228-4265) to find out how we can help them get a test kit and support them with any associated counseling regarding the results.

    SUGGESTED SUPPLEMENT SCHEDULE – BONE FRACTURES

    I have included all of the above supplements including recommended dosages plus more related to having an excellent diet in the table provided below.

    Description AM Noon PM Night Comments
    PRO-C 2 caps 2 caps 2 caps Take with meals or with snack.
    Bone Guardian 

    Bone Guardian Caps (easier to absorb)

    3 tabs

    3 caps

     

    3 caps

    3 tabs

    3 caps

    Take with meals.

    Take with meals.

    Mighty Multi-Vite! or
    Multi Two -- Multivitamins
    2 caps or
    1 tab
    2 caps or
    1 tab
    Take with meals.
    Essential Fats plus E 2 softgel 2 softgel 2 softgel Take with meals.
    PROLYT - Proteolytic Enzyme Formula 2 caps 2 caps 2 caps 2 caps Take between meals.
    Buffered Vitamin C, Tablets -- 1,000 mg (1 gm) or Powder (1/4 tsp = 1 gm) 2 tabs or
    1/2 tsp
    2 tabs or
    1/2 tsp
    2 tabs or 1/2 tsp 2 tabs or 1/2 tsp Best with meals, but other times are okay. Start with 2 tabs or 1/2 tsp twice per day and add another 2 tabs or 1/2 tsp every few days until you are taking 8 tabs or 2 tsp per day.
    Vitamin D3 Plus 5,000 IU 1 softgel 1 softgel Take with meals. Reduce to 1 softgel after 2 months.
    Joint Health Formula 2 caps 2 caps 2 caps Take between meals and away from Bone Guardian.
    Magnesium Oil 10 pumps 10 pumps 10 pumps 10 pumps Spray on affected area – or nearby area.
    Rejuvenate! Plus or
    Rejuvenate! (original)
    1 scoop 1 scoop Take as a meal by itself or with fruit/berries.

    ADDITIONAL NUTRIENTS FOR BONE FRACTURES

    Additional nutrients that may be helpful include pH ADJUST (to balance excess acidity in the body),  Warrior Mist™ for pain relief (rub on adjacent area several times daily), Echinacea (as drops or capsules), N-Acetyl-L-Cysteine - NAC (2 gms per day), Progesterone Cream - for women (1/4–1/2 tsp twice daily), and Prescript-Assist™ probiotics (2 capsules daily) if on antibiotics.

    PROPER DIET IS ESSENTIAL

    Consume a diet that provides good amounts of protein which is needed by the body to support the healing of bone fractures. Eat meats, poultry and fish (e.g., sardines, salmon, mackerel) in the amount of a 5–10 ounces per day. Ensure a good intake of organic vegetables, including high levels of dietary fiber. Drink 16 oz per day of fresh vegetable juices from carrot, celery, beets, cabbage, etc.

    Other healthy foods (preferably organic) include fruits, whole grains (e.g., brown rice, millet, and quinoa), beans, nuts and seeds (sunflower, chia, flax, pumpkin, almond, walnut and sesame in small amounts — 2 or 4 ounces — are good). Try eating Hank's Vegetable Soup several times a week. Avoid all sweets (sugar), processed/refined foods (white bread and pasta), preservatives, and artificial flavors and colors. Vary your diet.

    HYDROTHERAPY (WATER THERAPY) FOR BONE FRACTURES

    An additional treatment that can be useful is hydrotherapy. In particular, hot and cold showers are a very effective way to move the blood and create circulation. This can speed up both detoxification and delivery of healing nutrients to the area of a bone fracture. Here's how to do this. Once daily, take a complete hot and cold shower. You will start with hot water for one minute, then cold for one minute. Repeat this seven (7) times so the shower should last about 15 minutes.

    Another time, daily, you can perform a complete hot and cold shower routine again or a partial one just applying the water directly to or near the area where there is a bone fracture. While you are doing both hot and cold showers, pay special attention to any affected area and massage it as vigorously as is safe and comfortable. If a shower is impossible, then alternate hot packs and ice packs on the area of the bone fracture.

    BONE FRACTURES – CONCLUSION

    By following the recommendations and suggested supplement schedule, healing time for bone fractures can be significantly reduced and fractures may heal more completely with fewer complications. By ensuring your body receives the proper nutrients it needs to heal itself, and by engaging in other relevant practices (e.g., hydrotherapy), you and/or your loved ones may be able to deal with bone fractures successfully, and continue a healthy, vibrant lifestyle.

    ADDITIONAL RESOURCES

    REJUVENATION PROGRAM PART 6 (INCLUDES HYDROTHERAPY)

    REJUVENATE!™ SUPERFOODS

    ULTIMATE PROTECTOR™

    "FRED'S FAVORITE VEGETABLE JUICE RECIPE: 'THE DOCTOR'"

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