Heard of RESTORE liquid mineral supplement? If not, you're about to discover something important for gut health.
RESTORE™ is formulated to help restore gut health. It works by strengthening the integrity of tight junctions in your intestinal wall.
Maintaining tight junctions is important because they protect your body from substances entering the blood stream. Restore also supports the communications systems of the bacteria in your microbiome.
Tight junctions are natural barriers protecting the lining of your gut barrier, organs such as kidneys and heart, and the blood-brain barrier thereby keeping out unwanted substances. Even as we take in nutrients from the GI tract, the function of tight junctions is maintaining the integrity of the gut wall and other barriers that protect the body.
These days, our gut membrane has a tough job keeping out unwanted substances. Because tight junctions are weakened by many things, including highly processed foods, especially those containing gluten and gliadin, the herbicide glyphosate (the primary ingredient in RoundUp weedkiller), and other exposures like electromagnetic fields (EMF) from digital devices and Wi-Fi networks.
As a result of weakened tight junctions, undesirable substances from food proteins, harmful chemicals and other toxins can slip though into our bloodstream. This can lead to a powerful immune response that can weaken immunity and cause significant inflammation. Foreign substances in the bloodstream can also result in extreme food allergies and food sensitivities to various toxins entering the body.
We live in an age in which our microbiome health is under assault. Studies show our ancient ancestors had 20,000–30,000 different strains of beneficial bacteria in their GI tracts. Many people today have just 5,000 or less. Why is that?
There are many reasons for low microbiome diversity. These reasons include antiobiotic use (both from pharmaceuticals and foods), glyphosate (which essentially acts like an antibiotic), processed foods (especially those containing gluten and gliadin), and systemic degradation of the gut environment rendering it less hospitable for maintaining health populations of gut flora.
These impacts are significant because diversity in your microbiome not only supports gut health, but also appropriate brain health, immune system health, and overall vitality. Restore acts as a "microbiome fertilizer" helping establish and maintain healthy microbiota.
In fact, Restore contains important "redox" molecules produced millions of years ago by existing soil bacteria. These molecules are an important part of communications systems within the body between gut bacteria and with the body's mitochondria. These communication systems play an important role in establishing proper homeostasis throughout the body.
REASONS TO USE RESTORE™
There are important reasons to try Restore—whether or not you experience significant gut health issues. These reasons include:
• Maintaining strong tight junctions for mega membrane health, and helping the body restore tight junction integrity
• Creating an environment in which beneficial bacteria can thrive
• Boosting microbiome diversity
• Healing the gut
• Mitigating the adverse effects substances like antibiotics, gluten/gliadin, glyphosate, and GMOs on microbiome health
• Supporting immune system function
• Protecting integrity of blood-brain barrier
Other benefits include support for respiratory wellness, enhancing mental clarity, and promoting proper homeostasis throughout the body.
For all these reasons and more, you should consider taking Restore. You can start by taking one teaspoon or less daily, and gradually increasing your dose to one tablespoon or more.
I have taken Restore daily for more than two years, and benefit greatly from it. The most noticeable effects are a complete cessation of spring allergies (after two decades of worsening symptoms), greater clarity of thinking, and improved overall well being. I have seen other people get good results with a variety of conditions from dysbiosis to gluten/gliadin sensitivity.
MORE ABOUT RESTORE™
You can learn more about Restore on our website. Also, the Restore website offers in-depth information and videos. Here is how the Restore website and Dr. Zach Bush describe the formula:
Restore is a dietary supplement supplying first line defense against daily exposure to environmental and food-borne factors. It helps create an optimal environment or ecology in the gut membrane for beneficial or "good" bacteria to flourish. Beneficial gut flora protect your immune system and maintain health. Restore is a scientifically proven soil-derived mineral supplement designed to support protection of the intestinal walls.
Restore protects the entire gastrointestinal (GI) tract against agricultural herbicides, antibiotics, GMOs, gluten, and food-borne toxins. It helps create an environment in which 20,000–30,000 different strains of beneficial gut bacteria can thrive. This is a far different mode of action from probiotics, most of which contain just 3–30 strains of beneficial bacteria.
Restore helps create a strong immune system along with proper gut function. Microbiome balance and tight junction integrity are known to constitute a significant part of the immune system. They directly affect DNA transcription of cells to promote optimal health and prevent a leaky gut syndrome, thereby improving gut intelligence.
Seventy percent (70%) of our immune system is found in our gut. We need tens of thousands different strains of good gut bacteria to support a healthy immune system. Clinical experience, in addition to cell culture studies, support the theory that Restore’s proprietary formula creates the optimal environment in the gut to create a tight junction barrier and maintain our health and wellness.
Restore is a daily liquid supplement designed to support the protection of the entire gastrointestinal (GI) tract against agricultural herbicides, antibiotics, GMOs, gluten and food-borne toxins by helping to create an environment where between 20,000-30,000 different strains of good gut bacteria thrive. Most probiotics on the market contain fewer than 24 different strains of good gut bacteria.
Restore is ideal for individuals suffering from gut health issues. Yet, it is also excellent for supporting and maintaining gut health generally. That is the reason we at HPDI consider Restore important enough to designate as a foundational supplement, one of the top six supplements you need for good health.
Given the safety and effectiveness of Restore, there is broad applicability for its use. This is especially true because gut and microbiome health are under constant assault. These assaults range from multiple environmental and lifestyle factors—including poor diets high in processed foods, antibiotics in pharmaceuticals and animal foods—to massive glyphosate (herbicide) contamination of foods, soils, air, and water.
Let Restore be your first line of defense against assaults on your gut health, tight junctions, microbiome diversity, and immune function. As it says on the bottle, "Complete well-being begins in the gut."
We recently added a category of products for Gut Health to HPDI's foundational supplements program. We did this not only because there is a documented increase in gut-related health issues, but also because we hear about gut health issues from our clients and resellers. They desire effective means for solving the gut health problems prevalent today.
One of the biggest gut health problems we see today is leaky gut syndrome. The syndrome goes by other names and encompasses various symptoms. These symptoms broadly encompass food allergies, sensitivities, and intolerances.
Yet, the symptoms can also include low energy, fatigue, immune disorders, as well as obesity and blood sugar issues. It also encompasses celiac disease and certain brain disorders.
In fact, most these gut-related conditions and symptoms today go beyond what was historically meant by "leaky gut syndrome." Today leaky gut and the conditions associated with it largely seem to relate to a combination of factors, including modern agricultural methods, use of antibiotics and certain other pharmaceuticals, and toxic chemicals in foods and the environment.
Studies show the herbicide glyphosate adversely impacts gut health.
TOXIC INDUSTRIAL AGRICULTURE
Agriculture was not so long ago an organic affair. Chemical fertilizers were unknown, soils were healthier, and crops were at least non-GMO.
Things got worse with the introduction of chemical fertilizers, herbicides, and pesticides. The green revolution of the 1960s brought more changes, including the rise of monoculture crops and more dependence on chemicals.
Chemicals used in agriculture destroy soil microbes. These chemicals induce plant growth without simultaneously improving the quality of the soil. Consequently, the result is depletion of nutrients in soils. This has been proven by measurable declines in vitamins, minerals, and other nutrients in food crops.
When soils are continuously depleted and are nutrients are not replaced or augmented (as in Biodynamic agriculture, for example), soils have fewer nutrients. Eventually crops grown in these soils will be nutrient-poor and therefore not optimal for health. Nutrient declines in soils are significant, and soils continue to be depleted of nutrients.
The combination of chemical fertilizers, herbicides, and pesticides has created an unsustainable system of agriculture that does not produce nutritious food crops. Herbicides such as 2,4-D and atrazine, and pesticides like DDT (which remains in soils) are examples of chemicals that can significantly harm human and environmental health.
The introduction of genetically modified (GMO) crops has accelerated the negative effects of industrialized farming methods. This is especially true in terms of the lowering soil-quality and adversely impacting soil microbes, reducing nutrient levels in crops, and both directly and indirectly harming human health.
GMO crops have not been properly tested for safety. The dangers of GMO crops are significant. Bt corn is a crop whose genetic modification is associated directly with gut health issues (see charts below). Bt corn was created to damage the intestines of insects, but that also damages the health of the human gut.
When combined with specialized herbicides designed for use on GMO crops, the dangers of GMOs increase significantly. The primary herbicide used for GMO crops is glyphosate, which is a mineral chelator, endocrine disruptor, and biocide with antibiotic effects that kill bacteria (beneficial and harmful) indiscriminately leading to an imbalanced human microbiome.
Glyphosate appears to be associated with an increasing number of adverse health conditions partly because many health problems can be caused or exacerbated by nutrient deficiencies, endocrine disruption, microbiome imbalances, and other toxic effects. These health conditions include leaky gut syndrome which not only may result from an imbalanced microbiome, but also from a loosening of the necessarily tight junctions in the gut wall that protect us from exposure to foreign proteins not unlike the blood-brain barrier protects our brain.
Use of the herbicide glyphosate has increased dramatically in recent years. Glyphosate is the primary (but by no means the only) ingredient in the herbicide RoundUp.
Glyphosate kills plants including weeds, and it does this partly by acting as a mineral chelator that prevents the uptake of nutrients by plants. This starves the plant until it dies. However, plants genetically modified to withstand glyphosate still contain fewer nutrients and are therefore less nutritious.
Moreover, any glyphosate you consume acts as a chelator in your body that blocks your uptake of minerals and nutrients. This will not be good, especially if the GMO foods you consume are already nutrient deficient. Glyphosate also interferes with how you uptake and process nutrients (like manganese) in ways that guarantee depletion in the body, as will be discussed further below).
Source: N. L. Swanson, "Genetically Modified Organisms and the Deterioration of Health in the United States" (2013)
A major reason for increasingly larger applications of glyphosate on crops is the rise of glyphosate-resistant "super weeds." This was not predicted to happen, but clearly it is happening. Thus, the "solution" to the development of supersedes has been simply to apply more glyphosate. This means greater amounts of poison in crops, and of course, greater profits for the herbicide company.
The problem is that glyphosate is extremely toxic. If there were a perfect storm scenario for herbicide use, then glyphosate would be one component of it. Many scientists are concerned about it, including former genetic engineers like Thierry Vrain, who now advocates growing and consuming organic foods (see more below).
Increased use of glyphosate will in turn accelerate the rise of super-resistant weeds, and accelerate damage to the health of those who consume it.
Not to mention the unknown health risks of the genetically modified (GMO) crops themselves, which are sprayed with glyphosate. How would you be able to tell which is more damaging to health, the toxins embedded in GMO crops or the sprays that soak both GMO and non-GMO crops alike. None have been properly tested, or test results are hidden or suppressed.
Beyond all this, non-GMO crops like wheat, oats, barley, beans, and nuts are routinely sprayed with glyphosate at the end of the season as a means to dry these crops to make harvesting easier. So much for trying to eat verified non-GMO.
You're likely getting a lot of glyphosate in your diet...unless you eat 100% organically grown foods that are not contaminated with glyphosate by direct spraying, spraying for the purposes of drying, or from drift related to nearby spraying.
And with increased levels of spraying to apply more of this herbicide, the likelihood is you're getting glyphosate not only from foods, but also from a contaminated water supply (wells, rivers, streams), and from rainfall (with more than 65% of rain samples testing positive).
Scientists may disagree on the level of veracity of the article, and quibble over the finer points of statistical correlation. Meanwhile, people are getting sicker, not healthier. And that is the point.
If indeed glyphosate is impacting human health adversely at even a fraction of the levels argued by Swanson, then individuals should reduce their consumption of GMO foods as much as possible to avoid health consequences.
Foods containing GMOs should be clearly labeled, like they are in many other countries. Consumers have a right to know if foods contain GMO. There is no valid objection to labeling since many other (and far less harmful) ingredients in foods are labeled. This is a transparency issue. It is the least consumers deserve.
In July 2016, the US enacted the so-called DARK Act, which requires labels for GMO products. However, this fast-tracked law is far weaker than the Vermont law that preceded it. The US law preempts state laws. It represents a poor attempt to address consumers' desire for labeling of GMO foods. It offers no standard labeling requirements, nor any means to enforce compliance for companies that fail to label. And while some may consider the US law progress for consumers, consider that in Europe GMO labeling went into effect back in 1997 – nearly 20 years ago.
In addition, proper scientific testing of the health effects of GMOs and in particular the herbicide glyphosate, as well as the adjuvants and surfactants contained in glyphosate-containing products—and how these ingredients act synergistically—must be carried out. Consumers should never be guinea pigs when science is available that can protect them and help them make informed decisions.
Not unlike tobacco companies that suppressed and downplayed the harm of their products, today's purveyors of agricultural chemicals (and especially GMOs and glyphosate) are not particularly concerned about the adverse health effects of their products. In fact, it appears to be just the opposite, as studies indicating harmful effects frequently have been suppressed.
Several of the studies used to indicate safety of GMOs were short-term studies (three months) conducted by companies that make and sell the products themselves without peer review or release of data. Whereas longer-term, independent studies indicate probable harm to health, therefore showing the precautionary principle was disregarded in approving GMOs for human consumption.
In order for consumer to protect themselves, GMO labeling is a minimum measure. Most nations already either require clear labeling or ban GMOs.
AVOID ANTIBIOTICS IN FOODS AND ELSEWHERE
The use of antibiotics in livestock results in a tainted food supply. This means that foods ingested contain antibiotics that damage and destroy beneficial microbes in the human gut. This contributes to reduced microbiome diversity and paves the way for a takeover by harmful bacteria.
Then there is the overuse of antibiotics in human medicine. The use of antibiotics significantly damages microbiome health and diversity. The importance of the microbiome for human health is such that antibiotic use that kills beneficial bacteria and imbalances the gut flora is proven to reduce overall health and can contribute to major health problems throughout life. This is especially true when antibiotics are used in childhood when the microbiome is establishing itself.
Glyphosate is not considered an antibiotic per se, but it exerts antibiotic-like effects. That is, glyphosate destroys microbes by acting on the Shikimate pathway, and therefore acts like an antibiotic. This pathway is not present in human beings, but is present in plants and most microbes important for the health of the human gut.
Glyphosate interferes with the synthesis by gut bacteria of aromatic amino acids (including tyrosine and tryptophan) as well as methionine. This leads to shortages in critical neurotransmitters such as serotonin and melatonin as well as folate.
There is evidence to show that glyphosate produces resistance to antibiotic drugs, just as overuse of antibiotics themselves contributes to the increase of so-called "superbugs," or bacteria resistant to most or all antibiotics. This fact is another reason glyphosate contributes to the health problems relating to antibiotic use and to gut health issues, in particular.
The overuse of antibiotics both in humans and animals is an ongoing problem with many authorities calling for a reduction in use so that antibiotics are not rendered useless by the development of antibiotic-resistant strains of bacteria.
Current policies regarding antibiotics virtually guarantee that not only will microbiome health be harmed by the consumption of antibiotic tainted foods and by the use of antibiotics too easily prescribed, but also that harmful bacteria will become stronger rendering antibiotics less useful in applications where they are truly needed.
An interesting fact in this regard is that Pseudomonas aeruginosa, a gram-negative bacteria, is a major problem in hospitals today due to its resistance to multiple antibiotics. It is one of only three bacterial species that can break down glyphosate. However, it produces formaldehyde as a by-product. Formaldehyde is a well-established neurotoxin. It is likely that the growth of this harmful bacteria is stimulated by the presence of glyphosate in the gut.
Avoidance of antibiotics in foods and when not medically necessary are ways individuals can help keep themselves healthy.
While this article deals primarily with the topic of gut or gastrointestinal health, it is noteworthy that glyphosate is considered to be an endocrine disruptor.
Endocrine disruption is associated with birth defects, reproductive problems (like infertility), breast cancer, and developmental problems in babies and children before and after birth, as well as a host of other health effects.
Endocrine disruptors are common in the environment, and we have written about them in previous posts. Glyphosate's role as an endocrine disruptor is important not only because it is another harmful element among its many dangers, but also simply because of its ubiquitousness in the environment.
The amount of glyphosate spray in the US and the world in extraordinary. As weeds have become resistant to glyphosate (leading to the rise of super weeds), the solution has been to spray more of it. Therefore, the amounts to which individuals are exposed have skyrocketed along with the increase in its application on crops and elsewhere.
Also, as noted, the practice of spraying glyphosate as a desiccating agent on non-GMO crops (such as wheat, oats, sugar cane, and peanuts) contributes significantly to human exposure. So too does "household" use in gardens and use by municipalities for spraying to decrease "weeds" in public places, such as parks and schools.
NUTRIENTS, HORMONES, AND NEUROTRANSMITTERS DISRUPTED BY GLYPHOSATE
Dr. Stephanie Seneff is a leading researcher in the area of the harmful effects of glyphosate. The following YouTube presentation by Dr. Seneff and Dr. Sachin Patel (interviewer) provides a wealth of information for the reader and is highly recommended: https://www.youtube.com/watch?v=TpoGUPwe40c
In Dr. Seneff's presentations she has pointed out that the following nutrients, hormones, and neurotransmitters are disrupted by glyphosate:
Folate, Vitamin K, Vitamin A, Vitamin D, and cobalamin (Vitamin B12).
Aromatic amino acids and methionine
Iron, manganese, cobalt, selenium, zinc, and sulfur
Serotonin, melatonin, dopamine, epinephrine
Melanin (skin tanning agent), thyroid hormone
NAD, glutathione (key antioxidant defenses)
Clearly it would be wise to take in foods and nutritional supplements that could replete the body with these substances.
In order to compensate for these effects of glyphosate Dr. Seneff recommends the following supplements:
GLYPHOSATE DISRUPTS PROTEINS AND ENZYMES RELYING ON GLYCINE
Recently, Dr. Seneff and collaborators have identified the fact that glyphosate – a glycine amino acid based molecule – can disrupt a large number of enzymes in the body by inserting itself into proteins during the synthesis process where glycine would normally be inserted. When this happens, the function of the enzyme is completely negated. For further details see: https://www.youtube.com/watch?v=snNRfAfSeUk
LEAKY GUT AND BT TOXINS
Another class of worrisome genetically modified crops are Bt corn and other Bt crops (cotton, potato, and soy). Note that there are also glyphosate tolerant/resistant strains of corn (maize), so all types of GMO corn are potentially hazardous to health.
Bt corn is a variant of maize genetically altered to express proteins from the bacterium Bacillus thuringiensis. Thousands of different Bt strains exist that produce proteins toxic to insect pests. Particular strains are chosen to target specific plant pests, such at the European Corn Borer (ECB).
When an insect consumes Bt-containing plant tissues, one or more Bt proteins become activated in its gut, creating toxins that paralyze its digestive system and form holes in its gut wall.
Bt toxins bind to receptors in the insect's gut. This causes the gut wall to break down and allows toxins, as well as normal gut bacteria to enter the insect's body. Toxins and bacteria proliferate in the insect's body causing death. Notably, many insects have developed resistance to glyphosate, just as have weeds.
It has been noted by commentators that the human digestive system appears to be damaged in a similar way by proteins in Bt corn. In any event, as the number of acres planted with Bt corn increases, it appears that human digestive disorders also increase.
Source: N. L. Swanson, "Genetically Modified Organisms and the Deterioration of Health in the United States" (2013)
Disorders of the digestive system associated with Bt toxins not only include irritable bowel syndrome (IBS) and constipation, but also Crohn's Disease and Ulcerative Colitis.
Source: N. L. Swanson, "Genetically Modified Organisms and the Deterioration of Health in the United States" (2013)
While the effects of the Bt toxin are different than those of glyphosate and other chemicals in glyphosate-containing crop chemicals, the fact is that evidence shows that the Bt toxins appear to adversely impact gut health.
KEY TAKEAWAY: CONSUME 100% ORGANIC DIET
Among key takeaways from examining the literature of problems associated with antibiotic use, as well as with the chemicals associated with modern agriculture and genetically modified foods (i.e., glyphosate and other herbicides, pesticides, and various surfactants and adjuvants used with them): Choose to eat organic foods as much as possible for best health.
Only by consuming organic foods can individually significantly reduce the amount of glyphosate, pesticides, antibiotics, and other harmful chemicals in the diet to support good health in general, and gut health in particular. Organic foods are also more nutrient dense, and therefore more nutritious.
After it is understood how current industrial agricultural methods contribute to damaging human health, then organic foods can be seen as a solution helping ensure avoidance of most or many of harmful elements in foods.
Organically grown foods may be tainted by drift or by toxins in the soil existing before the adoption of organic farming methods. Yet, the amounts of such toxins will be significantly reduced overall by consuming organic foods. The longer-term solution is adoption of organic methods (and corresponding reductions in use of chemicals and GMOs in agriculture) that will result in a cleaner, safer food supply for all.
Some say that organic foods are no better, or cost too much, or do not improve health. But the truth is that they are better, should not cost more, and are far more sustainable for human and planetary health. In fact, at this point in time, consuming organic foods may be the only practical solution for avoiding health problems, especially gut-health problems, associated with industrialized, chemically based agricultural methods.
Growing food yourself is another option, as is purchasing organic or locally grown organically grown produce at your Farmer's Market. These foods will not be sprayed with toxins and will not suffer the same level of nutrient declines found in conventional produce.
Between consuming foods you grow, purchasing organic or non-sprayed produce locally or at natural foods stores, emphasizing grass-fed, free-range animal products (e.g., eggs and meats), and reducing meals at restaurants that serve conventional foods, you can largely bypass or reduce the toxicity and gut-health issues associated with the toxins and GMOs in foods sold in grocery stores and ubiquitous in our food distribution system.
A 100% organic diet is recommend, entirely possible, and at the very least a worthy goal. It will pay dividends in terms of good health and how you feel.
Wheat stands out as a singular food to avoid. It been hybridized beyond all recognition with many genes being added because wheat genes are additive. The wheat protein gluten has been linked to many types of health problems.
Gluten has long been a problem for gut health. Now with glyphosate being sprayed directly on wheat crops (as well as oats, sugar cane, and peanuts) as a desiccating agent, it seems that opening tight junctions in the gut and then having exposure to gluten is a prescription for disaster.
Glyphosate increasingly is sprayed on wheat (a non-GMO crop) for drying before harvest. How does poisoning wheat this way make sense?
Some commentators (like Wheat Belly author William Davis, MD) show that gluten is linked with obesity, diabetes, celiac disease, and many others.
Avoidance of wheat, gluten, and other simple carbohydrates is a good idea if you would maintain and retain good gut health.
Celiac disease has significantly increased with the practice of spraying glyphosate on wheat.
"The pathologies to which glyphosate could plausibly contribute, through its known biosemiotic effects, include inflammatory bowel disease, obesity, depression, ADHD, autism, Alzheimer’s disease, Parkinson’s disease, ALS, multiple sclerosis, cancer, cachexia, infertility, and developmental malformations." (Entropy2013, 15(4), 1416-1463; doi:10.3390/e15041416)
Industrial agriculture, including the practices associated with the cultivation of GMO crops, harms the soils and human health.
Dangers to human health from industrial agriculture and GMOs includes harm to gastrointestinal health. This encompasses many conditions, including Leaky Gut Syndrome.
Leaky gut does not always result from a single cause, but can involve multiple factors, including exposure to glyphosate (and its adjuvants), Bt toxins, depleted nutrient levels, wheat and wheat protein (gluten/gliadin) exposure, microbiome imbalances or disruption, antibiotic use or consuming foods containing antibiotics, other chemical exposures, and additional factors.
Ways to avoid leaky gut: 1) Consume a 100% organic diet, 2) Avoid GMOs, 3) Avoid antibiotics, 4) Maintain a healthy microbiome, 5) Avoid wheat and simple carbohydrates (and simple sugars), 6) Improve nutrient levels through diet and dietary supplements, 7) Use specific supplements that help restore and maintain gut health 7) Detoxify on a regular basis using juices, herbs, and other practices.
We will continue writing articles for blog series on the topic of gut health. In coming months, we will write about various means for improving gastrointestinal structure and function. These means include restoring tight junctions in the gut using Restore (lignite formula).
I came away from Dr. Bassler's talk with a new understanding of who we are and how we are influenced by bacteria. The fact that our bodies house ten times the number of bacteria than the number of cells in our bodies and 100 times the amount of DNA compared to our human DNA is very impressive!! Of particular note was the fact that bacteria conduct both intraspecies and interspecies communication using carbon-based hormones.
Since that time my company switched to a soil-based organisms (SBO) probiotic formula called Prescript-Assist as our main probiotic formula. The formula includes a "prebiotic" called leonardite.
Leonardite is a natural form of humates that is completely organic in nature and provides ideal conditions for "good" bacteria to grow. It is a soft, waxy, black or brown, shiny, vitreous mineraloid that is easily soluble in alkaline solutions.
Leonardite is an oxidation product of lignite, a soft, brown combustible sedimentary rock formed from naturally compressed peat. Lignite has a carbon content of 25–35% and embedded in the carbon are special carbon based molecules that were produced by soil bacteria millions of years ago.
The amazing part of this story is that Dr. Zachary Bush – a medical doctor with extensive experience in cancer research and mitochondria chemistry – made an accidental and instant connection between the special carbon molecules of lignite and special redox molecules found in mitochondria.
Based upon his recognition of these similar molecules, he developed a formula using the lignite bacterial produced carbon molecules. He found that by adding certain trace minerals and amino acids under special conditions these carbon molecules were activated.
Upon giving his formula to human beings, Dr. Bush discovered dramatic and rapid increases in beneficial gut bacterial counts. That is, the human microbiome was significantly affected in a positive way. This is particularly important since it is known that the human gastrointestinal tract houses about seventy percent of our immune system.
The most amazing part of the story was then discovered. That is when the formula (called RESTORE) was given, the tight junctions in the gut were restored to their optimal condition and "leaky gut" disappeared.
What makes this discovery so special is that "leaky gut" is caused by certain toxic bacteria, gluten, antibiotics, medical anti-inflammatories, and especially the herbicide glyphosate (RoundUp) used for genetically modified (GMO) food crops. This "leaky gut" condition is endemic in our society and getting worse as we continue to take in these toxic substances in ever increasing amounts. In Dr. Bush's experience with a very broad range of conditions, healing began to occur very quickly when RESTORE is taken.
Additionally, Dr. Bush found that when the tight junctions in the gut were restored to their optimal condition, all of the other tight junctions in the body were restored as well. These include tight junction in the blood brain barrier, the kidney tubules, blood vessels, etc. As a result many conditions in the body dramatically improved.
Dr. Bush discovered that almost all conditions of poor health are caused by chronic inflammation and he has stated that chronic inflammation is caused by a lack of communication within the cells of the body. He has clearly seen that RESTORE reinstates proper communication between the cells and greatly reduces inflammatory conditions!
HOW EXCITING!!! Based upon this almost unbelievable discovery we have decided to carry RESTORE on our retail website and take it ourselves!!!
HPDI has always offered high-quality probiotic formulas, such as Polydophilus. We are now very pleased to offer Prescript-Assist™, one of the very best broad spectrum probiotic and prebiotic formulas available.
Probiotics are valued for their capacities to improve health. They boost intestinal health by increasing populations of beneficial bacteria, counterbalance the adverse effects of antibiotics on gut flora, help fight yeast infections, and much more.
Current research shows that increasing population of "good-for-you" bacteria can exert beneficial effects beyond what anyone believed or predicted less than a decade ago. Some of these benefits are truly remarkable and the list of benefits seems to grow every year.
BENEFITS OF PROBIOTIC SUPPLEMENTS & CULTURED FOODS
Benefits reported from probiotics include 1) relief of stress, anxiety, and depression, 2) mood improvement via gut-brain signaling, 3) protection against free radicals, 4) anti-inflammatory properties, 5) improvement of glucose tolerance, 6) reduction of upper respiratory tract infections, 7) allergy prevention, 8) cholesterol reduction, 9) beneficial effects in liver disease, and 10) many other health benefits.
It appears that the range of benefits of probiotics (including probiotic supplements) is so great and that more benefits (and their mechanisms) have yet to be discovered.
People recognize that probiotics are found in a variety of foods with live or active bacteria cultures (often found in cultured or fermented foods), which include yogurt, sauerkraut, miso soup, buttermilk, and gouda cheese. Many traditional cultures emphasize the consumption of cultured foods.
Consuming cultured foods is a great way to obtain probiotics naturally from your diet. However, taking a probiotic supplement offers additional benefits beyond the benefits obtained from dietary sources. These benefits can include a wider range and greater number of beneficial bacteria, ease of use, standardized amounts to assess intake, and ensuring high intake of probiotics when dietary sources like cultured foods are not readily available or desirable.
Given the very broad range of benefits relating to use or consumption of probiotics, it is little wonder that they are so widely used, and so commonly recommended. Indeed, we recommend regular use of probiotic for a variety of health-related reasons. Our health recommendations often include the probiotic supplements we offer either as an "enhancement" supplement or sometimes as a "condition specific" formula depending on the health status of the individual and the conditions s/he seeks to address.
While cultured foods are often simply part of a traditional diet, people also consume these foods or take probiotics for specific reasons, such as when their gastrointestinal tract is not functioning well. Other times are when individuals experience GI related symptoms, including abdominal bloating or discomfort, indigestion, nausea, bowel irregularity, flatulence, as well as general malaise, fatigue, or weakness.
Because imbalances in the makeup of healthy bacteria found in the intestines can be the cause of health issues related to the digestive tract, it is important that if an individual decides to take a probiotic supplement that the supplement be of the highest quality and the greatest effectiveness.
INTRODUCING PRESCRIPT-ASSIST™: A BROAD SPECTRUM PROBIOTIC & PREBIOTIC
Not long ago, HPDI decided to make Prescript-Assist™ available to our customers. We did this because we believe Prescript-Assist is hands down one of the best probiotic formulas available. Here are reasons that anyone who takes (or considers taking) probiotic supplements would benefit greatly from taking Prescript-Assist.
29 STRAINS OF SYMBIOTIC MICROFLORA IN ONE PROBIOTIC FORMULA
Prescript-Assist™ is a proprietary, broad spectrum formula providing 29 naturally resilient strains that support your body's natural intestinal balance. Having so many strains means that this formula better reflects the great microbial diversity of the intestines vs typical probiotic products. In fact, more than 1,000 different species of microbes inhabit the human gut. Also of note: Prescript-Assist™ contains Bacillus subtilis, which is a well-proven probiotic species found in traditional foods.
Most probiotic formulas provide only lactic-acid based bacteria. Lactic-acid bacteria are important, but they are hardly the only or the most important probiotic for humans. They are also quite fragile, and must be refrigerated if they are to remain viable.
Here (below) is a complete list of the strains provided by Prescript-Assist. That is, each 600 mg capsule of Prescript-Assist includes the following microorganisms (and leonardite, a prebiotic):
It is notable that science has discovered that the number of bacterial cells in our bodies is more than ten times the number of human cells. This collection of living cells is essentially an extension of our own bodies, and has been labeled the "human microbiome."
It is clear that the number and types of species found in the gut can be a primary difference between an optimal digestive system and immune system, and those less than optimally functional. In scientific studies, individuals exhibiting higher levels of gastrointestinal distress and gut irregularities have been found to have a correspondingly lower variety of beneficial bacteria in the intestines.
Prescript-Assist™ is a next-generation, clinically proven probiotic supplement designed to to ensure maximum viability of the many organisms it provides. The formula offers inherent viability because the species it provides naturally adapted for survival in the human GI tract. That is, these 29 species are environmentally based (SBO) species drawn from the terrestrial microbiome where they have prospered and adapted for millenia to beneficially coexist with humans.
This inherent viability avoids the need for nano-encapsulation or hard-shelled enteric-coated capsules, which both are essentially attempts to force viability of probiotic species rather than utilizing hardy strains that are naturally pre-adapted to our bodies.
Thus, typical probiotic formulas contain low viability lactic acid bacteria that must be protected by technologies such as micro-encapsulation due to their inherent fragility. These fragile bacteria have a difficult time surviving because they are readily destroyed within the acidic environment of the stomach. While patented enteric coatings can help survival rates, the provision of high-viabiltiy organisms that reach the intestines intact due to the inherent strength of their natural spore structure makes more sense as a means to protect against degradation in the stomach and intestinal tract.
Bottom line: Prescript-Assist™ provides bacteria that reach the intestines intact due to the fact that the spore structure protects against degradation or destruction by stomach acids.
SHELF STABILITY (NO REFRIGERATION NEEDED)
Prescript-Assist offers unparalleled shelf stability. It is well known that conventional probiotics (i.e., lactic acid bacteria) are readily damaged, degraded, and destroyed by the heat and pressure of the manufacturing process. They are also degraded by exposure to light and by temperature changes. Because they lack shelf stability, if they are not kept refrigerated, they often cannot provide a sufficient quantity of organisms by the time of ingestion.
In contrast, Prescript-Assist features probiotic bacteria protected by a durable seed-like structure, so that they are better safeguarded against environmental factors, including heat, pressure, light, or temperature variability. Indeed, testing confirms that the probiotic bacteria in Prescript-Assist remain 95% viable two years after their date of manufacture without any need for refrigeration.
Most probiotic formulas do not contain any prebiotics, which are a food source for bacteria, and help accelerate their growth. Prescript-Assist uniquely contains leonardite, which is a prebiotic mixture of humic and fulvic acids, which allows the beneficial bacteria to proliferate and thrive.
Probiotic supplement formulas typically do not offer product-specific clinical studies validating their effectiveness. Prescript-Assist™ is different. It is supported by a peer-reviewed, placebo-controlled human clinical trial, and a one-year follow-up study that verifies its long-term efficacy.
Backed by Sound Science: Supported by peer-reviewed, published clinical studies.
Inherent Organism Viability: A matrix of superior, highly resilient microflora whose organic, seed-like structures survive the early GI tract to thrive in the intestines.
Contains Bacillus subtilis: A proven probiotic species found in traditional foods.
29 Symbiotic Organisms: A balanced formulation specially selected to mimic the natural flora found in traditional and paleolithic diets.
Proven Shelf Stable: With variations of less than 5% over two years from date of manufacture when stored at 98°F / 37°C .
Supported By Prebiotics.
Gluten-Free, Dairy Free, and Vegan.
DIRECTIONS FOR USE
As a dietary supplement for adults, take 1–2 capsules per day, or as directed by your health care professional. May be taken with or without food.
No refrigeration necessary. Store under normal conditions.
Routine viability testing confirms greater than 95% viability two years after date of manufacture — without refrigeration. See individual package for expiry.
CONCLUSION: A VIABLE PROBIOTIC FOR ALL SEASONS
We at HPDI have always striven to bring our customers the best products and formulas available whether or not we ourselves design and produce them.
When a formula like Prescript-Assist™ comes along (which is not every day), we are often quick to recognize its benefits, which in this case are many. We offer this unique formula knowing that it is safe, effective, and can help improve the health of our customers.
We also know that Prescript-Assist can be used effectively in combination with our other supplements (i.e., foundational supplements and superfoods), including formulas we design specifically for GI health like Intestinal Rejuvenation Formula.
Indeed, we ourselves take Prescript-Assist™ and experience major health benefits. In addition, we personally witness and hear from many individuals who take the formula based on our recommendations. The results reported are excellent.
Messaoudi, M, et al. Beneficial psychological effects of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in healthy human volunteers. Gut MicrobesJuly/August 2011; 2:4, 256-261.
Sudo N, Chida Y, Aiba Y, Sonoda J, Oyama N, Yu XN, et al. Postnatal microbial colonization programs the hypothalamic-pitutary-adrenal system for stress response in mice. J Physiol 2004; 558:263-75.
Sudo N. Stress and gut microbiota: does postnatal microbial colonization programs the hypothalamicpituitary- adrenal system for stress response? Int Congr Ser 2006; 1,287:350-4.
Messaoudi M, et al. Assessment of psychotropic-like properties of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in rats and human subjects. Br J Nutr 2011; 105:755–64.
Martarelli, D et al. Effect of a probiotics intake on oxidant and antioxidant parameters in plasma of athletes during intense exercise training. Curr Microbiol. 2011 June; 62(6): 1689–96.
Gleeson, M et al. Daily probiotic’s (Lactobacillus casei Shirota) reduction of infection incidence in athletes. Int J Sport Nutr Exercise Metab. 2011;21:55–64.